tert-butyl N-[N'-[5-[5-[5-[bis[(2-methylpropan-2-yl)oxycarbonylamino]methylideneamino]pentoxy]-2-carbamoyl-4-[2-(dimethylamino)ethylcarbamoyl]phenoxy]pentyl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamimidoyl]carbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tert-butyl N-[N'-[5-[5-[5-[bis[(2-methylpropan-2-yl)oxycarbonylamino]methylideneamino]pentoxy]-2-carbamoyl-4-[2-(dimethylamino)ethylcarbamoyl]phenoxy]pentyl]-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamimidoyl]carbamate
• 化学式: C₄₄H₇₅N₉O₁₂
• 分子量: 922.1
• InChiKey: GSRIFFMAHIPWRV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.6
• 重原子数：
  65
• 可旋转键数：
  31
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.68
• 拓扑面积：
  272
• 氢给体数：
  6
• 氢受体数：
  15

文献信息

• Compounds for use in treatment of mucositis
  申请人：Innovation Pharmaceuticals Inc.

  公开号：US10206894B2

  公开（公告）日：2019-02-19

  The present invention provides methods for treating and/or preventing mucositis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.

  本发明提供了用本文公开的一种或多种化合物或其药学上可接受的盐，或包含这些化合物的组合物治疗和/或预防粘膜炎的方法。
• COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS
  申请人：Cellceutix Corporation

  公开号：EP2709619B1

  公开（公告）日：2017-10-11
• Compounds For Use In Treatment Of Mucositis
  申请人：Cellceutix Corporation

  公开号：US20170224640A1

  公开（公告）日：2017-08-10

  The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.
• Compounds For Use In Treatment of Mucositis
  申请人：Innovation Pharmaceuticals Inc.

  公开号：US20180064664A1

  公开（公告）日：2018-03-08

  The present invention provides methods for treating and/or preventing mucositis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.
• US8802683B2
  申请人：——

  公开号：US8802683B2

  公开（公告）日：2014-08-12