3-Aethyl-5,5-dimethylhydantoin | 37021-15-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 3-Aethyl-5,5-dimethylhydantoin
• 英文别名: 3-Ethyl-5,5-dimethylimidazolidine-2,4-dione
• CAS: 37021-15-1
• 化学式: C₇H₁₂N₂O₂
• mdl: MFCD11731550
• 分子量: 156.184
• InChiKey: PUOUKAVMFCKYKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.714
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE
  申请人：SHY Therapeutics LLC

  公开号：US20170174699A1

  公开（公告）日：2017-06-22

  Provided herein are compounds that inhibit the phosphorylation of MAPK and thus are useful in compositions and methods for treating cancer and inflammatory disease.

  本文提供了抑制MAPK磷酸化的化合物，因此可用于治疗癌症和炎症性疾病的组合物和方法。
• ORGANIC COMPOUNDS AND THEIR USES
  申请人：Brandl Trixl

  公开号：US20100204159A1

  公开（公告）日：2010-08-12

  The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.

  本申请描述了对人类疾病的治疗、预防和/或改善有用的有机化合物。
• N-halamines compounds as multifunctional additives
  申请人：Board of Regents, The University of Texas System

  公开号：US10138379B2

  公开（公告）日：2018-11-27

  The present invention is a composition and method for making and using a rechargeable multifunctional additive that reduce the formation of biofilms on a surface, the additive can also remain photo and thermally stable by synthesizing one or more N-halamine compounds and adding one or more N-halamine biocidal compounds to a target material prior, during or after the target material is made. The resultant material can be used directly to provide antimicrobial functions and control biofilm formation, or the material can be further processed into an article.

  本发明是通过合成一种或多种 N-卤胺化合物，并在目标材料制造之前、期间或之后将一种或多种 N-卤胺杀菌化合物添加到目标材料中，从而制造和使用一种可再充电的多功能添加剂的组合物和方法，该添加剂可减少表面生物膜的形成，还能保持光稳定性和热稳定性。制成的材料可直接用于提供抗菌功能和控制生物膜的形成，也可进一步加工成物品。
• Role of Proteoglycans in Drug Dependence
  申请人：Sanna Pietro P.

  公开号：US20100199361A1

  公开（公告）日：2010-08-05

  The invention provides methods of preventing or treating drug addiction, or ameliorating the craving for an addictive drug, as well as compounds, peptides, and pharmaceutical compositions that may be used to prevent or treat drug addiction or ameliorate the craving for an addictive drug. The invention also provides methods for identifying agents that may be used to prevent or treat drug addiction, or ameliorate the craving for an addictive drug.
• ROLE OF PROTEOGLYCANS IN DRUG DEPENDENCE
  申请人：SANNA Pietro P.

  公开号：US20120174240A1

  公开（公告）日：2012-07-05

  The invention provides methods of preventing or treating drug addiction, or ameliorating the craving for an addictive drug, as well as compounds, peptides, and pharmaceutical compositions that may be used to prevent or treat drug addiction or ameliorate the craving for an addictive drug. The invention also provides methods for identifying agents that may be used to prevent or treat drug addiction, or ameliorate the craving for an addictive drug.

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