1-(2-Methylpentyl)pyrrole-2,5-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 1-(2-Methylpentyl)pyrrole-2,5-dione
• 英文别名: 1-(2-methylpentyl)pyrrole-2,5-dione
• 化学式: C₁₀H₁₅NO₂
• 分子量: 181.23
• InChiKey: VSXWHBKYYWDHDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• SHORT INTERFERING NUCLEIC ACID (SINA) COMPOSITIONS
  申请人：Sirna Therapeutics, Inc.

  公开号：EP3358013B1

  公开（公告）日：2020-06-24
• PHOTOSENSITIVE RESIN COMPOSITION FOR FORMING MEMBER HAVING CURVED SHAPE, PHOTOSENSITIVE RESIN FILM FOR FORMING MEMBER HAVING CURVED SHAPE USING SAID COMPOSITION, AND LENS MEMBER MANUFACTRED USING SAID COMPOSITION OR SAID FILM
  申请人：HITACHI CHEMICAL COMPANY, LTD.

  公开号：US20160209743A1

  公开（公告）日：2016-07-21

  [Problem] To provide a photosensitive resin composition for forming a member having a curved shape, which is soluble in an alkaline aqueous solution, and with which a pattern can be formed comparatively freely, wherein a lens member formed by using the said composition is excellent in heat resistance, formability of a curved shape, and transparency. [Solution] The said photosensitive resin composition for forming a member having a curved shape comprises (A) a polymer, (B) a polymerizable compound having a group which thermally reacts with the said polymer, and (C) a polymerization initiator.
• [EN] NOVEL PH-SWITCHABLE PEPTIDES FOR MEMBRANE INSERTION AND PORE FORMATION<br/>[FR] NOUVEAUX PEPTIDES À PH COMMUTABLE POUR UNE INSERTION DANS UNE MEMBRANE ET UNE FORMATION DE PORES
  申请人：MERCK SHARP & DOHME

  公开号：WO2014126828A1

  公开（公告）日：2014-08-21

  Disclosed herein is a pH-switchable pore formation (PSPF) peptide comprising one or more amino acids in peptide sequence whose charge state and hydrophobicity are pH-dependent, wherein the peptide can bind to a biological membrane upon contact and form pores on the membrane at pH of less than about 7, and wherein the peptide forms substantially no pores on the biological membrane at pH of greater than about 7. Also disclosed is a modular composition comprising: a) one or more PSPF peptides, which may be the same or different; b) a single stranded or double stranded oligonucleotide; and c) one or more linkers, which may be the same or different.