(4-Amino-2-carbamimidoylphenyl) pentanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: (4-Amino-2-carbamimidoylphenyl) pentanoate
• 英文别名: (4-amino-2-carbamimidoylphenyl) pentanoate
• 化学式: C₁₂H₁₇N₃O₂
• 分子量: 235.28
• InChiKey: JDFBXIHDHHEGBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  102
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• PEPTIDE DERIVATIVES AND USE THEREOF AS CARRIERS FOR MOLECULES IN THE FORM OF CONJUGATES
  申请人：Vect-Horus

  公开号：US20140243499A1

  公开（公告）日：2014-08-28

  The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB).
• US9328143B2
  申请人：——

  公开号：US9328143B2

  公开（公告）日：2016-05-03