4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-(1,1-dihydroxythietan-3-yl)-2-methylbenzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-(1,1-dihydroxythietan-3-yl)-2-methylbenzamide
• 化学式: C₂₁H₁₈Cl₂F₄N₂O₄S
• 分子量: 541.3
• InChiKey: JABMBVBIDSKKQX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  34
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  92.2
• 氢给体数：
  3
• 氢受体数：
  10

文献信息

• USE OF AMINOACETONITRILE DERIVATIVES AGAINST ENDOPARASITES
  申请人：Zoetis LLC

  公开号：US20140243408A1

  公开（公告）日：2014-08-28

  The present invention relates to a method of treating a parasitic infection in an animal, particularly a filarial endoparasitic infection, comprising administering an effective amount of a Formula (I) compound or a Formula (II) compound stereoisomer thereof, or veterinarily acceptable salt of said compound or stereoisomer thereof, or in combination with at least one additional veterinary agent, wherein: R 1 , R 2 , R 3 , R 4 , R 5 , R 1a , R 1b , R 1c , R 1d , R 1e are as described herein.
• US8962681B2
  申请人：——

  公开号：US8962681B2

  公开（公告）日：2015-02-24