Benzamido octanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzamido octanoate
• 英文别名: benzamido octanoate
• 化学式: C₁₅H₂₁NO₃
• 分子量: 263.33
• InChiKey: IKCJGTNDKFLAHR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  55.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Method of treating cancer
  申请人：Intensity Therapeutics, Inc.

  公开号：US10888618B2

  公开（公告）日：2021-01-12

  The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an intracellular penetration enhancing agent, and optionally in further combination with local administration of an immunotherapeutic agent, such as a cancer vaccine or NKT agonist. The invention also provides a method for treating cancer using an intracellular penetration enhancing agent. The methods of the invention aim to substantially kill and/or destroy the target tumor cells, as well as those cancerous cells that have metastasized to other parts of the body.

  本发明提供了一种使用联合给药策略治疗癌症的方法，该策略结合了治疗剂和细胞内渗透增强剂的局部联合给药，并可选择进一步结合免疫治疗剂（如癌症疫苗或 NKT 激动剂）的局部给药。本发明还提供了一种使用细胞内渗透增强剂治疗癌症的方法。本发明的方法旨在杀死和/或消灭目标肿瘤细胞以及转移到身体其他部位的癌细胞。
• METHOD OF TREATING CANCER
  申请人：Intensity Therapeutics, Inc.

  公开号：US20140248211A1

  公开（公告）日：2014-09-04

  The invention provides a method for treating cancer using a coadministration strategy that combines local codelivery of a therapeutic agent and an intracellular penetration enhancing agent, and optionally in further combination with local administration of an immunotherapeutic agent, such as a cancer vaccine or NKT agonist. The invention also provides a method for treating cancer using an intracellular penetration enhancing agent. The methods of the invention aim to substantially kill and/or destroy the target tumor cells, as well as those cancerous cells that have metastasized to other parts of the body.
• US9351997B2
  申请人：——

  公开号：US9351997B2

  公开（公告）日：2016-05-31
• US9636406B2
  申请人：——

  公开号：US9636406B2

  公开（公告）日：2017-05-02