US9205085, Msx-185

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: US9205085, Msx-185
• 英文别名: N-[[4-[[(5-fluoropyridin-2-yl)amino]methyl]phenyl]methyl]-5-methylpyridin-2-amine
• 化学式: C₁₉H₁₉FN₄
• 分子量: 322.4
• InChiKey: GABFGFWTJDGLBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  49.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• TRICYCLIC AMINO CONTAINING COMPOUNDS FOR TREATMENT OR PREVENTION OF SYMPTOMS ASSOCIATED WITH ENDOCRINE DYSFUNCTION
  申请人：EMORY UNIVERSITY

  公开号：US20140248236A1

  公开（公告）日：2014-09-04

  The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.
• Tricyclic Amino Containing Compounds for Treatment or Prevention of Symptoms Associated with Endocrine Dysfunction
  申请人：Natchus Michael G.

  公开号：US20160058761A1

  公开（公告）日：2016-03-03

  The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.
• US9205085B2
  申请人：——

  公开号：US9205085B2

  公开（公告）日：2015-12-08