2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(4-hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol
• 化学式: C36H36O4
• 分子量: 532.7
• InChiKey: WPBLXBMCCKKZDM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.44
• 重原子数：
  40
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• COMBINATORIAL COMPOSITIONS AND METHODS FOR TREATMENT OF MELANOMA
  申请人：THE GENERAL HOSPITAL CORPORATION

  公开号：US20160008332A1

  公开（公告）日：2016-01-14

  Embodiments described here are combinatorial compositions and methods using these compositions for treating melanomas having activated mutations. The compositions comprises combinations of inhibitors of a MAPK pathway, ERK inhibitors, EGFR inhibitors, oxidative phosphorylation (OXPHOS) inhibitors, inhibitors of B-Raf, mitochondrial inhibitors, c-KIT inhibitors, MEK inhibitors and tigecycline or a derivative thereof.
• US9937161B2
  申请人：——

  公开号：US9937161B2

  公开（公告）日：2018-04-10
• [EN] COMBINATORIAL COMPOSITIONS AND METHODS FOR TREATMENT OF MELANOMA<br/>[FR] COMPOSITIONS COMBINATOIRES ET MÉTHODES DE TRAITEMENT D'UN MÉLANOME
  申请人：GEN HOSPITAL CORP

  公开号：WO2014138338A1

  公开（公告）日：2014-09-12

  Embodiments described here are combinatorial compositions and methods using these compositions for treating melanomas having activated mutations. The compositions comprises combinations of inhibitors of a MAPK pathway, ERK inihbitors, EGFR inhibitors, oxidative phosphorylation (OXPHOS) inhibitors, inhibitors of B-Raf, mitochondrial inhibitors, c-KIT inhibitors, MEK inhibitors and tigecycline or a derivative thereof.