Magnesium;4-carboxy-3-methylphenolate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Magnesium;4-carboxy-3-methylphenolate
• 英文别名: magnesium;4-carboxy-3-methylphenolate
• 化学式: C16H14MgO6
• 分子量: 326.58
• InChiKey: ZNDZVBRSZCYFOH-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  1.15
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  121
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Method for treating a protozoal infection
  申请人：Reid Christopher Brian

  公开号：US10561650B2

  公开（公告）日：2020-02-18

  A method for reducing motility and number of L. donovani cells, said method comprising contacting the L. donovani cells with an effective amount of a composition, the composition comprising a combination of metronidazole and itraconazole, wherein the effective amount is sufficient to reduce motility of the L. donovani cells.

  一种降低唐诺瓦尼氏菌细胞活力和数量的方法，所述方法包括将唐诺瓦尼氏菌细胞与有效量的组合物接触，所述组合物包括甲硝唑和伊曲康唑的组合，其中有效量足以降低唐诺瓦尼氏菌细胞的活力。
• US20140271923A1
  申请人：——

  公开号：US20140271923A1

  公开（公告）日：2014-09-18
• METHOD FOR TREATING A PROTOZOAL INFECTION
  申请人：REID Christopher Brian

  公开号：US20160354370A1

  公开（公告）日：2016-12-08

  Patients inflicted with various clustering chronic diseases require treatment with multiple drugs having distinct mechanisms of action. Accordingly, patients with multiple conditions suffer from cumulative side effects of multiple drugs as well as drug-drug interactions. Embodiments, agents, compounds or drugs of the present invention, such as sesquiterpenes, e.g., Zerumbone, replace an equal or larger number of approved drugs during patient treatment. Examples of disorders prevented or ameliorated by administration of the formulations of this invention include but are not limited to inflammatory diseases that may be, oncological, genetic, ischemic, infectious, neurological, hematological, ophthalmological, rheumatoid, orthopedic, neurological, hematological, kidney, vascular, dermatological, gynecological, or obstetric. The present invention further relates to a method of identifying agents, compounds or drugs useful in preventing or treating CDCP related diseases and conditions as well as other disorders, diseases and conditions treatable or preventable by the same agents, compounds or drugs.
• Compositions of Natural Extracts and Use Thereof in Methods for Preventing or Treating Diseases
  申请人：REID Christopher Brian

  公开号：US20190224193A1

  公开（公告）日：2019-07-25

  A composition for reducing miR-3120 expression in a cell or tissue of a subject comprises at least one oil or extract selected from a group comprising an orange, frankincense and cannabis oil or extract. A method for reducing miR-3120 expression in a cell or tissue of a subject comprises administering to the subject a composition comprising at least one oil or extract selected from the group comprising an orange, frankincense and cannabis oil or extract.
• [EN] COMPOSITIONS OF NATURAL EXTRACTS AND USE THEREOF IN METHODS FOR PREVENTING OR TREATING DISEASES<br/>[FR] COMPOSITIONS À BASE D'EXTRAITS NATURELS ET LEUR UTILISATION DANS DES MÉTHODES DESTINÉES À PRÉVENIR OU À TRAITER DES MALADIES
  申请人：REID CHRISTOPHER BRIAN

  公开号：WO2017161387A1

  公开（公告）日：2017-09-21

  Synthetic drug development is slow and costly, often running into the billions of dollars. While the benefits of various abundant and inexpensive natural products, including natural oils and extracts, have been postulated and speculated upon for centuries, there has been very little success in achieving national approval (e.g. FDA approval) of natural compounds so that they can be used to benefit animals and patients. As many natural products are often complex and heterogenous, appropriate technologies for rapidly and efficiently predicting efficacy and toxicity of such natural compounds has been sorely lacking. Thus, there has been a long held and still unmet need to determine and teach appropriate health, veterinary, and medical uses for an orange, frankincense and cannabis products in a costeffective and efficient manner. Accordingly, the present invention teaches compositions, manufacture, products, and methods of use, prevention and treatment using at least one extract selected from the group comprising orange, frankincense, cannabis or other natural oil or extract or at least one substance or compound isolated from said at least one oil or extract (e.g. a cannabinoid, sesquiterpene, monoterpene, an ester, ether, aldehyde, phenylpropene, alcohol, ketone, phenol, etc.), so as to benefit medicine, human health and veterinary care. For example, the present invention teaches, the use of at least one extract selected from the group comprising orange, frankincense, cannabis or other natural oil or extract or at least one substance or compound isolated from said at least one oil or extract to reduce miR21 expression and thus treat/prevent cancer and psoriasis.