4-But-2-ynyl-6-oxocyclohexa-1,3-diene-1-sulfonyl chloride

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 磺酰卤
• 英文名称: 4-But-2-ynyl-6-oxocyclohexa-1,3-diene-1-sulfonyl chloride
• 英文别名: 4-but-2-ynyl-6-oxocyclohexa-1,3-diene-1-sulfonyl chloride
• 化学式: C₁₀H₉ClO₃S
• 分子量: 244.69
• InChiKey: AQSOTYBZTWKFRL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  59.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS
  申请人：Galderma Research & Development

  公开号：EP2968314A2

  公开（公告）日：2016-01-20
• US20140275108A1
  申请人：——

  公开号：US20140275108A1

  公开（公告）日：2014-09-18
• [EN] NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS<br/>[FR] NOUVEAUX COMPOSÉS BENZÈNESULFONAMIDES, LEUR PROCÉDÉ DE SYNTHÈSE ET LEUR UTILISATION EN MÉDECINE AINSI QUE DANS DES PRODUITS COSMÉTIQUES
  申请人：GALDERMA RES & DEV

  公开号：WO2014140861A2

  公开（公告）日：2014-09-18

  Provided herein are novel benzenesulfonamide compounds having a structure of formula (I), as well as to the method for synthesizing same and to the use thereof in pharmaceutical compositions to be used in human or veterinary medicine, as well as to the use thereof. Also provided herein are methods of using the disclosed pharmaceutical compositions for the treatment of neuroinflammatory skin diseases such as acne.