The invention provides compositions for stimulating the formation of one or more extracellular matrix components that contain a lipoaminoacid derivative of the tripeptide carnosine such as N-Octanoyl Carnosine. Also provided are compositions containing N-Octanoyl Carnosine in combination with selected tripeptide and/or tetrapeptides as well as pharmaceutical and/or cosmetic compositions containing such compositions. The invention further provides methods of using the compositions and compositions of the invention to treat, alleviate, and/or ameliorate a symptom, condition, disorder, or disease of the skin or mucosa, wherein the symptom, condition, disorder, or disease is associated with changes in extracellular matrix components.
本发明提供了刺激一种或多种细胞外基质成分形成的组合物,这些组合物含有三肽肉碱的脂
氨基酸衍
生物,如 N-
辛酰肉碱。本发明还提供了含有 N-
辛酰肉碱与所选三肽和/或四肽的组合物,以及含有此类组合物的药物和/或化妆品组合物。本发明进一步提供了使用本发明的组合物和组合物治疗、减轻和/或改善皮肤或粘膜的症状、状况、失调或疾病的方法,其中症状、状况、失调或疾病与细胞外基质成分的变化有关。