2,2,6,6-tetramethyl-1-tosyloxy-4-piperidone | 7166-32-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2,6,6-tetramethyl-1-tosyloxy-4-piperidone
• 英文别名: 2,2,6,6-tetramethyl-1-(toluene-4-sulfonyloxy)-piperidin-4-one；2,2,6,6-Tetramethyl-1-[(4-methylbenzene-1-sulfonyl)oxy]piperidin-4-one；(2,2,6,6-tetramethyl-4-oxopiperidin-1-yl) 4-methylbenzenesulfonate
• CAS: 7166-32-7
• 化学式: C₁₆H₂₃NO₄S
• 分子量: 325.429
• InChiKey: ASZCMEBDDSDCCE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  72.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,2,6,6-tetramethyl-1-tosyloxy-4-piperidone 在 氢氧化钾 作用下， 以 甲醇 为溶剂， 反应 0.5h， 以100%的产率得到2,2,6,6-tetramethyl-1-azabicyclo[3.1.0]hexan-4-one
  参考文献：
  名称：

  Synthesis and properties of bicyclic aziridines, derivatives of triacetoneamine

  摘要：

  双环氮丙啶是 2,2,6,6-四甲基-4-哌啶酮（三丙酮胺）的衍生物，经酸处理后，N-C(1) 键或 N-C(2)键断裂，形成相应的吡咯烷、吡咯烷和哌啶。

  DOI：

  10.1007/s11172-007-0083-3

文献信息

• Formation of a bicyclic aziridine upon intramolecular nucleophilic substitution in triacetonamine derivatives
  作者：L. A. Krinitskaya

  DOI：10.1007/bf01557565

  日期：1987.7
• KRINITSKAYA L. A., IZV. AN CCCP. CEP. XIM.,(1987) N 7, 1685
  作者：KRINITSKAYA L. A.

  DOI：——

  日期：——
• HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS
  申请人：FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E. V.

  公开号：US20200231783A1

  公开（公告）日：2020-07-23

  The present invention relates to the use of halogen-free sulphonic acid esters and/or sulphinic acid esters as flame retardant and/or flame retardant synergists in plastics. The invention furthermore relates to the use of said compounds as radical generators in plastics, particularly in order to increase the molecular weight of the plastics, to branch and/or cross-link the plastics, to reduce the molecular weight of the plastics, to influence the molecular weight distribution of the plastics and to graft unsaturated monomers to the plastics. The present invention furthermore relates to the use of flame-retardant plastic compositions in the electrical or electronics industry, construction industry, transport industry, preferably automobiles, aircraft, trains and ships, for medical applications, for household appliances, vehicle parts, consumer products, packaging, furniture and textiles.
• US4250312A
  申请人：——

  公开号：US4250312A

  公开（公告）日：1981-02-10
• US4250313A
  申请人：——

  公开号：US4250313A

  公开（公告）日：1981-02-10