1-(2,4-difluorophenyl)-(R)-1-carbamoyloxyprop-(R)-2-yl carbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2,4-difluorophenyl)-(R)-1-carbamoyloxyprop-(R)-2-yl carbamate
• 英文别名: [(1R,2R)-1-carbamoyloxy-1-(2,4-difluorophenyl)propan-2-yl] carbamate
• 化学式: C₁₁H₁₂F₂N₂O₄
• 分子量: 274.224
• InChiKey: WXPFFELONAYIMT-ANLVUFKYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME
  申请人：BIO-PHARM SOLUTIONS CO., LTD.

  公开号：US20160023999A1

  公开（公告）日：2016-01-28

  The present invention provides a pharmaceutical composition for preventing and/or treating a epilepsy or epilepsy-related syndrome, for example an intractable epilepsy or its related syndrome such as drug-resistant epilepsy, comprising the phenyl alkyl carbamate compound as an active ingredient, and a use of the phenyl alkyl carbamate compound for preventing and/or treating epilepsy or epilepsy-related syndrome.

  本发明提供了一种药物组合物，用于预防和/或治疗癫痫或癫痫相关综合症，例如难治性癫痫或其相关综合症，如耐药性癫痫，该组合物包括苯基烷基氨甲酸酯化合物作为活性成分，以及苯基烷基氨甲酸酯化合物用于预防和/或治疗癫痫或癫痫相关综合症的用途。
• US9504668B2
  申请人：——

  公开号：US9504668B2

  公开（公告）日：2016-11-29
• [EN] PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME<br/>[FR] COMPOSÉS DE PHÉNYLALKYLCARBAMATE POUR UTILISATION DANS LA PRÉVENTION OU LE TRAITEMENT DE L'ÉPILEPSIE OU D'UN SYNDROME LIÉ À L'ÉPILEPSIE
  申请人：BIO PHARM SOLUTIONS CO LTD

  公开号：WO2014142519A1

  公开（公告）日：2014-09-18

  The present invention provides a pharmaceutical composition for preventing and/or treating a epilepsy or epilepsy-related syndrome, for example an intractable epilepsy or its related syndrome such as drug-resistant epilepsy, comprising the phenyl alkyl carbamate compound as an active ingredient, and a use of the phenyl alkyl carbamate compound for preventing and/or treating epilepsy or epilepsy-related syndrome.