methyl (E)-2-(hydroxymethyl)-3-oxo-2-(phenylmethoxycarbonylamino)hexadec-4-enoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl (E)-2-(hydroxymethyl)-3-oxo-2-(phenylmethoxycarbonylamino)hexadec-4-enoate
• 化学式: C₂₆H₃₉NO₆
• 分子量: 461.6
• InChiKey: BTYKNXIHPVNUBM-KNTRCKAVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  33
• 可旋转键数：
  19
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  102
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• US20140275591A1
  申请人：——

  公开号：US20140275591A1

  公开（公告）日：2014-09-18
• NOVEL COMPOUNDS
  申请人：AVANTI POLAR LIPIDS, INC.

  公开号：US20160340298A1

  公开（公告）日：2016-11-24

  Disclosed are compounds of the general formula I and II (as further defined herein) are useful in the production of inhibitors of sphingolipid synthesis the production of sphingolipids. Suitable sphingolipids, include, but not limited to, sphingosine and compounds incorporating sphingosine or that may use sphingosine as an intermediate or a starting material in their synthesis (including, but not limited to, sphingosine-1-P, ceramide, gangliosides and sphigomyelin). In one contemplated use, compounds of the general formula I and II are useful in the production of sphingosine. In another contemplated use, compounds of the general formula I and II are useful in the production of a sphingofugin. Methods of manufacturing each of the above compounds are also provided.
• US9403760B2
  申请人：——

  公开号：US9403760B2

  公开（公告）日：2016-08-02