2-[4-[(4-ethoxyphenyl)sulfonyl-methylamino]phenoxy]-N-methyl-N-(1-methylpiperidin-4-yl)acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[4-[(4-ethoxyphenyl)sulfonyl-methylamino]phenoxy]-N-methyl-N-(1-methylpiperidin-4-yl)acetamide
• 化学式: C₂₄H₃₃N₃O₅S
• 分子量: 475.6
• InChiKey: LSIFWLQOCMRFKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  33
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  87.8
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE
  申请人：Cunningham James

  公开号：US20130231332A1

  公开（公告）日：2013-09-05

  The present invention relates to compositions and methods for the treatment of infection by enveloped viruses, such as Ebola and Lassa fever viruses.
• Small Molecule Inhibitors of Ebola and Lassa Fever Viruses and Methods of Use
  申请人：President and Fellows of Harvard College

  公开号：US20160024066A1

  公开（公告）日：2016-01-28

  The present invention relates to compositions and methods for the treatment of infection by enveloped viruses, such as Ebola and Lassa fever viruses.
• US9193705B2
  申请人：——

  公开号：US9193705B2

  公开（公告）日：2015-11-24
• US9676763B2
  申请人：——

  公开号：US9676763B2

  公开（公告）日：2017-06-13
• [EN] SMALL MOLECULE INHIBITORS OF EBOLA AND LASSA FEVER VIRUSES AND METHODS OF USE<br/>[FR] PETITE MOLÉCULE INHIBANT LES VIRUS DE LA FIÈVRE D'EBOLA ET DE LASSA, ET PROCÉDÉS D'UTILISATION
  申请人：HARVARD COLLEGE

  公开号：WO2012031090A2

  公开（公告）日：2012-03-08

  The present invention relates to compositions and methods for the treatment of infection by enveloped viruses, such as Ebola and Lassa fever viruses.