N-[(2R)-1-[4-(4-piperidin-4-ylbutoxy)phenyl]propan-2-yl]butane-1-sulfonamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(2R)-1-[4-(4-piperidin-4-ylbutoxy)phenyl]propan-2-yl]butane-1-sulfonamide
• 化学式: C₂₂H₃₈N₂O₃S
• 分子量: 410.6
• InChiKey: GMBGBCOHMMSNPR-LJQANCHMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  28
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  75.8
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] COMPOUNDS AND COMPOSITIONS FOR DRUG RELEASE<br/>[FR] COMPOSÉS ET COMPOSITIONS POUR LIBÉRATION DE MÉDICAMENT
  申请人：INTERFACE BIOLOGICS INC

  公开号：WO2014139033A1

  公开（公告）日：2014-09-18

  The invention relates to compounds that include biologically active agents (e.g., compounds according to any of formulas (I) and (I-A) that can be used for effective drug release, e.g., as coatings for medical devices. Use of these compounds in the coating of surfaces can allow for long-term drug release as well as imparting uniform coatings with little phase separation compared to, e.g., the parent biologically active agent.