1-[(Z)-1-[1-(2,4-difluorophenyl)propan-2-yldiazenyl]oxyprop-1-enyl]-3-pyridin-2-ylurea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[(Z)-1-[1-(2,4-difluorophenyl)propan-2-yldiazenyl]oxyprop-1-enyl]-3-pyridin-2-ylurea
• 化学式: C₁₈H₁₉F₂N₅O₂
• 分子量: 375.4
• InChiKey: VDRDFIUIHFHTHR-TZLXXCRASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  88
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Methods Of Treating Dyskinesia And Related Disorders
  申请人：Melior Discovery, Inc.

  公开号：US20150231116A1

  公开（公告）日：2015-08-20

  The present disclosure describes compounds and pharmaceutically acceptable salts thereof and compositions and formulations comprising the same that are useful in methods of treating dyskinesia or related disorders, and methods for treating dyskinesia or related disorders.
• US9402830B2
  申请人：——

  公开号：US9402830B2

  公开（公告）日：2016-08-02
• [EN] METHODS OF TREATING DYSKINESIA AND RELATED DISORDERS<br/>[FR] MÉTHODES DE TRAITEMENT DE LA DYSKINÉSIE ET DE TROUBLES ASSOCIÉS
  申请人：MELIOR DISCOVERY INC

  公开号：WO2014145126A2

  公开（公告）日：2014-09-18

  The present disclosure describes compounds and pharmaceutically acceptable salts thereof and compositions and formulations comprising the same that are useful in methods of treating dyskinesia or related disorders, and methods for treating dyskinesia or related disorders.