1-(4-chlorobenzylidene)-2-(diphenylmethylene)hydrazine | 237403-23-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(4-chlorobenzylidene)-2-(diphenylmethylene)hydrazine
• 英文别名: N-[(4-chlorophenyl)methylideneamino]-1,1-diphenylmethanimine
• CAS: 237403-23-5
• 化学式: C₂₀H₁₅ClN₂
• 分子量: 318.805
• InChiKey: JSSRERJWBPJEOY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  24.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  二苯甲酮腙 、 4-氯苯甲醛 在 sulfated anatase-titania 作用下， 反应 0.01h， 以97%的产率得到1-(4-chlorobenzylidene)-2-(diphenylmethylene)hydrazine
  参考文献：
  名称：

  An expeditious and solvent free synthesis of azine derivatives using sulfated anatase–titania as a novel solid acid catalyst

  摘要：

  Solid acid catalyst sulfated anatase-titania (TiO2-SO42-) has been used for the synthesis of azine derivatives from benzophenone hydrazone and ketones/aldehydes by simple physical grinding. This sulfated titania gives an excellent yield with short reaction time and is an inexpensive, easily recyclable catalyst for this reaction. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2011.08.029

文献信息

• Capture of<i>In Situ</i>Generated Diazo Compounds or Copper Carbenoids by Triphenylphosphine: Selective Synthesis of<i>trans</i>- Alkenes and Unsymmetric Azines<i>via</i>Reaction of Aldehydes with Ketone-Derived<i>N</i>-Tosylhydrazones
  作者：Qiang Sha、Yifei Ling、Wenyong Wang、Yunyang Wei

  DOI：10.1002/adsc.201300302

  日期：2013.8.12

  AbstractCopper(II) acetylacetonate‐catalyzed Wittig olefination reactions of aldehydes with ketone‐derived N‐tosylhydrazones are reported. A series of tosylhydrazones was investigated and our results showed that the carbon number of the alkyl chain influences the E‐selecivity of the alkenes greatly. Alkenes could be obtained in moderate yields and excellent E‐selectivity when the carbon numbers were up to two. Under metal‐free conditions, triphenylphosphine was able to capture the in situ generated diazo compounds and the corresponding unsymmetrical azines were formed in good yields.magnified image