N-(4-tert-butylphenyl)-2-thiophen-2-ylacetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-tert-butylphenyl)-2-thiophen-2-ylacetamide
• 化学式: C₁₆H₁₉NOS
• 分子量: 273.4
• InChiKey: PWCRWVWRZLXAMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  57.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Low-molecular inhibitors of cytohesin-family guanine nucleotide exchange factors
  申请人：Famulok Michael

  公开号：US20090105286A1

  公开（公告）日：2009-04-23

  The invention relates to drugs and the use thereof, wherein said drugs contain compounds selected from a group comprising general formulas (1), (2), (3) and (4) and/or enantiomers, diastereomers or the pharmaceutically acceptable salts thereof. Said drugs are used for treating autoimmune and tumoral diseases and/or for immunosuppresion.
• USE OF CYTOHESIN INHIBITORS FOR CHEMICALLY INDUCING LONGEVITY
  申请人：Famulok Michael

  公开号：US20100048594A1

  公开（公告）日：2010-02-25

  The invention relates to compounds selected from among the group comprising general formulas (1), (2), (3), and/or (4) and/or the enantiomers, diastereomers, and derivatives thereof, and the pharmaceutically acceptable salts thereof for producing a medicament used for therapeutically and/or preventively treating disease and pathological conditions linked to regulation of the insulin and/or insulin-like growth factor (IGF) signalling pathway and/or for chemically inducing longevity.
• US7799915B2
  申请人：——

  公开号：US7799915B2

  公开（公告）日：2010-09-21
• US8163788B2
  申请人：——

  公开号：US8163788B2

  公开（公告）日：2012-04-24