3-[4-[(1Z,3Z,5Z)-6-[4-(diethylamino)phenyl]hexa-1,3,5-trienyl]pyridin-1-ium-1-yl]propyl-triethylazanium

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-[4-[(1Z,3Z,5Z)-6-[4-(diethylamino)phenyl]hexa-1,3,5-trienyl]pyridin-1-ium-1-yl]propyl-triethylazanium
• 化学式: C30H45N3+2
• 分子量: 447.7
• InChiKey: QIMSZQJQVSKLAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  33
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  7.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• COMPOUND FOR GENERATING SECOND HARMONIC OF LIGHT, DYE COMPOSITION FOR GENERATING SECOND HARMONIC OF LIGHT, AND CELL EXAMINATION METHOD
  申请人：KEIO UNIVERSITY

  公开号：US20160116460A1

  公开（公告）日：2016-04-28

  Provided are a compound that generates an SHG signal but has suppressed generation of a TPF signal. Also provided is a cell examination method using the same. A compound for generating a second harmonic of light, the compound being an azobenzene derivative of formula (1), or a salt thereof. (R1 and R2 independently represent alkyl groups having 6-12 carbon atoms, and R3 to R18 independently represent substituents selected from hydrogen, halogens, alkyl groups, alkoxy groups, aryl groups, amino groups, hydroxyl groups, nitro groups, and cyano groups, but R5 and R6, R9 and R10, R13 and R14, and R17 and R18 may combine together and form a ring structure having 5-7 carbon atoms. X represents —N+R19R20R21, a sulfonyl group, a carboxyl group, or an —OR group. Here, R19, R20, and R21 independently represent straight-chain or branched alkyl groups having 1-5 carbon atoms, and —OR represents a monovalent polyalkylene oxide group terminated by an alkoxy group. a is 0 or 1, b is 0 or 1, and n is an integer of 1-10.)

  提供了一种产生SHG信号但抑制TPF信号生成的化合物。还提供了一种使用该化合物的细胞检查方法。一种用于产生光的二次谐波的化合物，该化合物是具有式（1）的偶氮苯衍生物，或其盐。（R1和R2独立表示具有6-12个碳原子的烷基基团，R3至R18独立表示从氢、卤素、烷基基团、烷氧基团、芳基、氨基、羟基、硝基和氰基中选择的取代基，但R5和R6、R9和R10、R13和R14以及R17和R18可以结合在一起形成具有5-7个碳原子的环结构。X表示—N+R19R20R21、磺酰基、羧基或—OR基团。这里，R19、R20和R21独立表示具有1-5个碳原子的直链或支链烷基基团，—OR表示由烷氧基终止的一价多聚氧化烷基氧基团。a为0或1，b为0或1，n为1-10的整数。
• AMINO(OLIGO)THIOPHENE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE
  申请人：Loew Leslie M.

  公开号：US20090042227A1

  公开（公告）日：2009-02-12

  Amino(oligo)thiophene dyes useful for studying the electrophysiology of organelles, cells, and tissues are described. Compared to previously known dyes, the amino(oligo)thiophene dyes exhibit improved (faster) response to membrane potential changes, as well as the ability to be excited by 1064 nanometer femtosecond pulses. Methods of preparing the amino(oligo)thiophene dyes are also described.

  描述了用于研究细胞器、细胞和组织电生理学的氨基(寡聚)噻吩染料。与先前已知的染料相比，氨基(寡聚)噻吩染料对膜电位变化的响应更快，并且能够受到1064纳米飞秒脉冲的激发。还描述了制备氨基(寡聚)噻吩染料的方法。
• COMPOUND FOR GENERATING SECOND HARMONIC OF LIGHT, DYE COMPOSITION FOR GENERATING SECOND HARMONIC OF LIGHT, AND CELL EXAMINATION METHOD
  申请人：Keio University

  公开号：EP3000848A1

  公开（公告）日：2016-03-30

  Provided are a compound that generates an SHG signal but has suppressed generation of a TPF signal. Also provided is a cell examination method using the same. A compound for generating a second harmonic of light, the compound being an azobenzene derivative of formula (1), or a salt thereof. (R1 and R2 independently represent alkyl groups having 6-12 carbon atoms, and R3 to R18 independently represent substituents selected from hydrogen, halogens, alkyl groups, alkoxy groups, aryl groups, amino groups, hydroxyl groups, nitro groups, and cyano groups, R5 and R6, R9 and R10, R13 and R14, and R17 and R18 may combine together and form a ring structure having 5-7 carbon atoms. X represents -N+R19R20R21, a sulfonyl group, a carboxyl group, or an -OR group. Here, R19, R20, and R21 independently represent straight-chain or branched alkyl groups having 1-5 carbon atoms, and -OR represents a monovalent polyalkylene oxide group terminated by an alkoxy group. a is 0 or 1, b is 0 or 1, and n is an integer of 1-10.)

  提供了一种能产生 SHG 信号但抑制 TPF 信号产生的化合物。还提供了一种使用该化合物的细胞检查方法。一种用于产生光的二次谐波的化合物，该化合物是式 (1) 的偶氮苯衍生物或其盐。(R1和R2独立地代表具有6-12个碳原子的烷基，R3至R18独立地代表选自氢、卤素、烷基、烷氧基、芳基、氨基、羟基、硝基和氰基的取代基，R5和R6、R9和R10、R13和R14以及R17和R18可结合在一起并形成具有5-7个碳原子的环结构。X 代表-N+R19R20R21、磺酰基、羧基或-OR 基。这里，R19、R20 和 R21 独立地代表具有 1-5 个碳原子的直链或支链烷基，-OR 代表以烷氧基为末端的单价聚氧化亚烷基（a 是 0 或 1，b 是 0 或 1，n 是 1-10 的整数)。
• US8129532B2
  申请人：——

  公开号：US8129532B2

  公开（公告）日：2012-03-06
• US9709555B2
  申请人：——

  公开号：US9709555B2

  公开（公告）日：2017-07-18