N-butyl-3-(trifluoromethyl)benzene-1-sulfonamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-butyl-3-(trifluoromethyl)benzene-1-sulfonamide
• 英文别名: N-butyl-3-(trifluoromethyl)benzenesulfonamide
• 化学式: C₁₁H₁₄F₃NO₂S
• 分子量: 281.3
• InChiKey: PDPZYXBDZPXLPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• Isolation of N-Butylbenzenesulfonamide, Synthesis of Benzenesulfonamide Derivatives, and Use of N-Butylbenzenesulfonamide and Benzenesulfonamide Derivatives for Treating Benign Prostatic Hyperplasia and/or Prostate Carcinoma
  申请人：Matusch Rudolf

  公开号：US20080177107A1

  公开（公告）日：2008-07-24

  A process for isolating N-butylbenzenesulfonamide (NBBS) from biological material, the chemical synthesis of benzenesulfonamide derivatives, the use of NBBS and benzenesulfonamide derivatives for treating benign prostatic hyperplasia and/or prostate carcinomas the production of medicaments for the treatment thereof, and the use of NBBS and benzenesulfonamide derivatives as a lead substance in the development of active substances for treating benign prostatic hyperplasia and/or prostate carcinoma are provided.
• US7700654B2
  申请人：——

  公开号：US7700654B2

  公开（公告）日：2010-04-20