1,3-dimethyl-4,5-bis[3-(2-hydroxyethyl)ureido]imidazolidin-2-one | 312318-51-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 1,3-dimethyl-4,5-bis[3-(2-hydroxyethyl)ureido]imidazolidin-2-one
• 英文别名: 1,1'-(1,3-Dimethyl-2-oxoimidazolidine-4,5-diyl)bis[3-(2-hydroxyethyl)urea]；1-(2-hydroxyethyl)-3-[5-(2-hydroxyethylcarbamoylamino)-1,3-dimethyl-2-oxoimidazolidin-4-yl]urea
• CAS: 312318-51-7
• 化学式: C₁₁H₂₂N₆O₅
• 分子量: 318.333
• InChiKey: ODUIJMZKKQBFPW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  22
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  146
• 氢给体数：
  6
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1,3-dimethyl-4,5-bis(3-nitroso-3-ethylureido)imidazolidin-2-one 、 C.I.酸性橙108 以 水 为溶剂， 以76%的产率得到1,3-dimethyl-4,5-bis[3-(2-hydroxyethyl)ureido]imidazolidin-2-one
  参考文献：
  名称：

  A new approach to the synthesis of 1,3-dimethyl-4,5-disubstituted imidazolidin-2-ones

  摘要：

  1, 3 -Dimethyl-4,5-di(ureido)-substituted imidazolidin-2-ones have been synthesised by the nitrosation of 1,3-dimethyl-4,5-di(3-ethylureido)imidazolidin-2-one followed by the reactions of amines with the resulting 1,3-dimethyl-4,5-di(3-nitroso3-ethylureido)imidazolidin-2-one, and the structure of 1,3-dimethyl-4,5-di(3-ethylureido)imidazolidin-2-one has been confirmed by X-ray diffraction analysis.

  DOI：

  10.1016/j.mencom.2008.01.017

文献信息

• A new approach to the synthesis of 1,3-dimethyl-4,5-disubstituted imidazolidin-2-ones
  作者：Angelina N. Kravchenko、Elena Yu. Maksareva、Sergei V. Vasilevskii、Oleg V. Lebedev、Konstantin A. Lyssenko

  DOI：10.1016/j.mencom.2008.01.017

  日期：2008.1

  1, 3 -Dimethyl-4,5-di(ureido)-substituted imidazolidin-2-ones have been synthesised by the nitrosation of 1,3-dimethyl-4,5-di(3-ethylureido)imidazolidin-2-one followed by the reactions of amines with the resulting 1,3-dimethyl-4,5-di(3-nitroso3-ethylureido)imidazolidin-2-one, and the structure of 1,3-dimethyl-4,5-di(3-ethylureido)imidazolidin-2-one has been confirmed by X-ray diffraction analysis.