Pd-Catalyzed Suzuki–Miyaura and Hiyama–Denmark Couplings of Aryl Sulfamates
作者:Patrick R. Melvin、Nilay Hazari、Megan Mohadjer Beromi、Hemali P. Shah、Michael J. Williams
DOI:10.1021/acs.orglett.6b02330
日期:2016.11.18
Using a recently discovered precatalyst, the first Pd-catalyzed Suzuki–Miyaura reactions using aryl sulfamates that occur at room temperature are reported. In complementary work, it is demonstrated that a related precatalyst can facilitate the coupling of aryl silanolates, which are less toxic and reactive nucleophiles than boronic acids with aryl chlorides. By combining our results using modern electrophiles
The combination of diethyl phosphite and DMAP as ligands for nickel in an 8:1 THF-N-ethylpyrrolidinone (NEP) mixture allows a very efficient cross-coupling reaction to be performed between various functionalized arylzinc halides and aryl bromides, triflates and activated chlorides. The reaction proceeds at 25 degrees C within 1-48 h and requires only 0.05 mol % of the nickel catalyst.
Nickel or Iron Catalysed Carbon-Carbon Coupling Reaction of Arylenes, Alkenes and Alkines
申请人:knochel Paul
公开号:US20100184977A1
公开(公告)日:2010-07-22
Organozinc compounds of the type R
1
—Ar
1
—ZnY (1) can be reacted with different functionalized aryl halides R
2
—Ar
2
—X (2) in the presence of catalytic amounts of Ni or Fe in a polar solvent or solvent mixture to form polyfunctional biaryles of the type R
1
—Ar
1
—Ar
2
—R
2
(3). Organozinc compounds of the type (1) can be represented by the transmetallation reaction of functionalized aryl magnesium halides or lithium aryl compounds with e.g. ZnBr
2
.
5,6,7,12-Tetrahydrodibenz[c,f][1,5]azabismocines: Highly Reactive and Recoverable Organobismuth Reagents for Cross-Coupling Reactions with Aryl Bromides
作者:Shigeru Shimada、Osamu Yamazaki、Toshifumi Tanaka、Maddali L. N. Rao、Yohichi Suzuki、Masato Tanaka
DOI:10.1002/anie.200250205
日期:2003.4.25
NICKEL- ODER EISEN-KATALYSIERTE KOHLENSTOFF-KOHLENSTOFF-KUPPLUNGSREAKTION VON ARYLENEN, ALKENEN UND ALKINEN