diclofop | 75021-71-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diclofop
• 英文别名: (2S)-2-(4-(2,4-Dichlorophenoxy)phenoxy)propanoic acid；(2S)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid
• CAS: 75021-71-5
• 化学式: C₁₅H₁₂Cl₂O₄
• 分子量: 327.164
• InChiKey: OOLBCHYXZDXLDS-VIFPVBQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 diclofop 以 乙醚 为溶剂， 以89%的产率得到(2S)-2-[4-(2,4-二氯苯氧基)苯氧基]丙酸甲酯
  参考文献：
  名称：

  Nestler, Hans Juergen; Bieringer, Hermann, Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980, vol. 35, # 3, p. 366 - 371

  摘要：

  DOI：
• 作为产物：
  描述：

  4-(2,4-二氯苯氧基)苯酚 在 sodium hydroxide 、 potassium carbonate 作用下， 以 乙腈 为溶剂， 反应 23.5h， 生成 diclofop
  参考文献：
  名称：

  Nestler, Hans Juergen; Bieringer, Hermann, Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980, vol. 35, # 3, p. 366 - 371

  摘要：

  DOI：

文献信息

• Herbicide mixtures
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0351021A2

  公开（公告）日：1990-01-17

  A herbicidal composition comprises a carrier, a first herbicide and a second herbicide which is 3-(1-amino)ethylidene-5-methyl-furan-2,4-dione.

  一种除草剂组合物包括载体、第一除草剂和第二除草剂，第二除草剂是3-(1-氨基)乙烯基-5-甲基-呋喃-2,4-二酮。
• Novel esters as useful herbicidal compounds
  申请人：Coret Marcel Joel

  公开号：US20050282708A1

  公开（公告）日：2005-12-22

  The instant invention relates to the discovery of certain novel herbicidal esters of agriculturally active acids. These esters present agronomical advantages over traditional herbicidal products by presenting multiple herbicidal mechanisms that ensure activity over a broad weed spectrum while limiting the appearance of plant resistance.

  该瞬时发明涉及发现某些新颖的具有农业活性酸的除草酯类化合物。这些酯类化合物相对于传统的除草产品具有农学优势，通过呈现多种除草机制来确保对广泛杂草谱的活性，同时限制植物抗性的出现。
• Nanocellulose Derivative/Silica Hybrid Core-Shell Chiral Stationary Phase: Preparation and Enantioseparation Performance
  作者：Xiaoli Zhang、Litao Wang、Shuqing Dong、Xia Zhang、Qi Wu、Liang Zhao、Yanping Shi

  DOI：10.3390/molecules21050561

  日期：——

  Core-shell silica microspheres with a nanocellulose derivative in the hybrid shell were successfully prepared as a chiral stationary phase by a layer-by-layer self-assembly method. The hybrid shell assembled on the silica core was formed using a surfactant as template by the copolymerization reaction of tetraethyl orthosilicate and the nanocellulose derivative bearing triethoxysilyl and 3,5-dimethylphenyl groups. The resulting nanocellulose hybrid core-shell chiral packing materials (CPMs) were characterized and packed into columns, and their enantioseparation performance was evaluated by high performance liquid chromatography. The results showed that CPMs exhibited uniform surface morphology and core-shell structures. Various types of chiral compounds were efficiently separated under normal and reversed phase mode. Moreover, chloroform and tetrahydrofuran as mobile phase additives could obviously improve the resolution during the chiral separation processes. CPMs still have good chiral separation property when eluted with solvent systems with a high content of tetrahydrofuran and chloroform, which proved the high solvent resistance of this new material.

  通过逐层自组装方法，成功制备了在混合壳中具有纳米纤维素衍生物的核壳硅微球作为手性固定相。在硅核上组装的混合壳是通过表面活性剂作为模板，通过正硅酸四乙酯与带有三乙氧基硅烷基和3,5-二甲基苯基的纳米纤维素衍生物的共聚反应形成的。对所得的纳米纤维素混合核壳手性填料（CPMs）进行了表征并装入色谱柱，通过高效液相色谱法评估了其手性分离性能。结果表明，CPMs具有均匀的表面形貌和核壳结构。在正相和反相模式下，各种类型的手性化合物均被有效地分离。此外，作为流动相添加剂的氯仿和四氢呋喃可以明显提高手性分离过程中的分辨率。当用四氢呋喃和氯仿含量高的溶剂体系洗脱时，CPMs仍然具有良好的手性分离性能，这证明了这种新材料具有很高的耐溶剂性。
• A covalent organic framework for chiral capillary electrochromatography using a cyclodextrin mobile phase additive
  作者：Lidi Gao、Xuan Zhao、Shili Qin、Qing Dong、Xingfang Hu、Hongtao Chu

  DOI：10.1002/chir.23405

  日期：2022.3

  about 6.00 μm for the column prepared under the optimal conditions. Enantioseparation of 15 kinds of the single chiral compounds (histidine, arginine, lysine, leucine, threonine, methionine, valine, aspartic acid and glutamic acid, fipronil, diclofop, imazamox, quizalofop-p, imazethapyr, and acephate) and 3 kinds of mixed amino acids racemaces (valine, methionine, and glutamic acid) were performed with

  共价有机框架 (COF) 已被认为是毛细管电色谱 (CEC) 中很有前途的固相。制备了亚胺基COF涂层开管CEC柱（COF TpBD涂层OT柱），并通过X射线衍射（XRD）、傅里叶变换红外（FT-IR）光谱、热重分析（TGA）、氮气吸附/解吸（Brunauer-Emmett-Teller [BET]）和扫描电子显微镜（SEM）。结果表明，在最佳条件下制备的色谱柱柱效可达26776板/米，固定相厚度约为6.00 μm。15种单一手性化合物（组氨酸、精氨酸、赖氨酸、亮氨酸、苏氨酸、蛋氨酸、缬氨酸、天冬氨酸和谷氨酸、氟虫腈、双氯氟草胺、咪草啶酸、喹唑啉磷、咪草烟、采用COF TpBD包被的OT柱毛细管电色谱法（方法1）和COF TpBD包被的OT柱作为CEC的三种方法对3种混合氨基酸外消旋体（缬氨酸、蛋氨酸和谷氨酸）进行分析。分离通道，以及以 HP-β-CD 作为手性流动相添加剂的毛细管电泳 (CE)（方法
• New pyrazole derivatives, their production and uses
  申请人：HOKKO CHEMICAL INDUSTRY CO., LTD

  公开号：EP0202169A1

  公开（公告）日：1986-11-20

  As new compounds is provided a pyrazole derivative of the formula wherein R1a, R1b and R1c are each a hydrogen atom, a halogen atom, a nitro group, an amino group, a (lower) alkyl group, a halo-(lower)alkyl group, a (lower)alkenyl group, a (lower)alkynyl group, a (lower)alkylcarbonylamino group, a (lower)alkoxycarbonylamino group, a mono-(lower) alkylaminocarbonylamino group or a di-(lower)alkylaminocarbonylamino group; R2 is a hydrogen atom, a (lower)alkyl group, a (lower)alkenyl group, a (lower)alkynyl group, a (lower) alkoxy(lower)-alkyl group; a (lower)alkylthio(lower)alkyl group, a (lower)alkylcarbonyl(lower)alkyl group, a (lower) alkoxycarbonyl(lower)alkyl group, a (lower)alkylthiocarbonyl(lower) alkyl group, a cyano(lower)alkyl group, a (lower)alkylsulfonyl group, phenylsulfonyl group, a halogen-substituted phenylsulfonyl group or a (lower)alkyl-substituted phenylsulfonyl group, and X and Y are the same or different and each are a halogen atom. The pyrazoles are useful as herbicidal agentand may be produced by a variety of processes.

  作为新化合物，提供了一种吡唑衍生物，其式如下 其中 R1a、R1b 和 R1c 各为氢原子、卤素原子、硝基、氨基、（低级）烷基、卤代（低级）烷基、（低级）烯基、（低级）炔基、（低级）烷基羰基氨基、（低级）烷氧基羰基氨基、单（低级）烷基氨基羰基氨基或二（低级）烷基氨基羰基氨基； R2 是氢原子、(低级)烷基、(低级)烯基、(低级)炔基、(低级)烷氧基(低级)烷基；(低级)烷硫基（低级）烷基、(低级)烷羰基（低级）烷基、(低级)烷氧羰基（低级）烷基、(低级)烷硫基（低级）烷基、氰基（低级）烷基、(低级)烷磺酰基、苯磺酰基、卤素取代的苯磺酰基或(低级)烷基取代的苯磺酰基，以及 X 和 Y 相同或不同，且各自为卤素原子。吡唑可用作除草剂，并可通过多种工艺生产。