Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.
本发明公开了一种近红外
荧光成像剂,由
吲哚菁基荧光
染料和脂质体组成。本发明的近红外
荧光成像剂在前哨淋巴结中显示出较高的荧光强度和较长的锚定时间,因此可用于前哨淋巴结导航手术中检测前哨淋巴结。本发明还公开了一种
吲哚菁绿衍
生物,它特别适用于本发明的近红外
荧光成像剂。