tert-butylammonium tosylate | 63458-91-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tert-butylammonium tosylate
• 英文别名: tert-Butylammonium 4-toluenesulfonate；tert-butylammonium p-toluenesulfonate；t-butylammonium p-toluenesufonate；Tert-butylazanium;4-methylbenzenesulfonate；tert-butylazanium;4-methylbenzenesulfonate
• CAS: 63458-91-3
• 化学式: C₄H₁₁N*C₇H₈O₃S
• 分子量: 245.343
• InChiKey: PFULBERPJAXZOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.99
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  88.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  三甲基乙酰胺 、 羟基甲苯磺酰碘苯 以 乙腈 为溶剂， 反应 0.67h， 以90%的产率得到tert-butylammonium tosylate
  参考文献：
  名称：

  Direct conversion of aliphatic carboxamides to alkylammonium tosylates with [hydroxy(tosyloxy)iodo]benzene

  摘要：

  DOI：

  10.1021/jo00364a010

文献信息

• Non-covalent bonded 1D-3D supramolecular salts from tert‑butylamine and organic acids
  作者：Kaikai Hu、Peiqi Wang、Shouwen Jin、Bin Chen、Zhiyan Hu、Wen Ye、Ming Guo、Daqi Wang

  DOI：10.1016/j.molstruc.2021.132208

  日期：2022.4

  tert‑butylamine. The results unveil that among all the studied crystals the NH2 in L are protonated when the acids are deprotonated, the crystal packing is interpreted via the strong NH⋯O H-bond from the NH3+ and the deprotonated acids. Apart from the NH⋯O H-bond, the OH···O H-bonds were also existed at 6 and 12. Salts 1 - 2 had the NH⋯S H-bond. The NH···Cl H-bond existed in 7. Further view of the crystal packing

  广泛使用的最简单的大量伯胺叔丁胺与一组酸共结晶得到总共 14 种盐，这些盐已通过 XRD 技术、红外光谱和元素分析进行​​表征。还调查了它们的熔点。详细分析了它们的结构和超分子方面。所有化合物都是离子型的，H 会转移到叔丁胺的 NH 2上。结果表明，在所有研究的晶体中，当酸去质子化时，L 中的 NH 2被质子化，晶体堆积是通过来自 NH 3 +和去质子化酸的强 N H⋯O H 键来解释的。除了 NH⋯O H-bond，O H...O H-bonds也存在于6和12。盐1 - 2具有 N H⋯S H 键。N H···Cl H-键存在于7 . 晶体堆积的进一步观察表明，不同阵列的附加 CH 3 ...S, O...Cl, S...S, CH 3 ...C, CH 3 ...CH 3 , C H· ··O/CH 3 ···O, CH 2 ···Cl, CH···N, CH 3···π和π···π
• Iminophosphorane-mediated transformation of tertiary alcohols into t-alkylamines and their N-phosphorylated derivatives
  作者：Anna Koziara、Andrzej Zwierzak

  DOI：10.1016/s0040-4039(00)96903-x

  日期：1987.1

  Novel azidation of tertiary alcohols by means of trimetylsilyl azide in the presence of boron trifluoride etherate has been worked out. The Staudinger reaction of crude azides with triethyl phosphite affords the corresponding iminophosphoranes which can be directly transformed into diethyl N-(t-alkyl) phosphoroamidates or t-alkylamine tosylates.

  已经研究了在三氟化硼醚化物的存在下通过偏苯三甲硅烷基叠氮化物对叔醇的新型叠氮化。粗叠氮化物与亚磷酸三乙酯的施陶丁格反应得到相应的亚氨基正膦，其可直接转化为N-（叔烷基）氨基磷酸二乙酯或叔烷基胺甲苯磺酸盐。
• [EN] SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS<br/>[FR] SYNTHESE D'ALCOOLS AMINOÉTHER SECONDAIRES A ENCOMBREMENT STERIQUE
  申请人：EXXONMOBIL RES & ENG CO

  公开号：WO2005082835A1

  公开（公告）日：2005-09-09

  Severely sterically hindered secondary aminoether alcohols are prepared by reacting organic carboxylic, organic carboxylic acid halides, acid anhydrides or a ketene with an alkyl, alkaryl or alkylhalo sulfonate to yield a sulfonic. Carboxylic anhydride compound which is then reacted with a dioxane to cleave the ring of the dioxane, yielding a cleavage product which cleavage product is then aminated with an alkylamine and hydrolyzed with base to yield the severely sterically hindered secondary aminoether alcohol.

  通过将有机羧酸、有机羧酸酰卤、酸酐或酮烯与烷基、烷基芳基或烷基卤代磺酸酯反应，制备严重立体阻碍的二级氨醚醇，产物为磺酸。然后将羧酸酐化合物与二氧六环反应，裂解二氧六环的环，产生一个裂解产物，该裂解产物然后与烷基胺进行胺化反应，并用碱水解，得到严重立体阻碍的二级氨醚醇。
• Synthesis of Sterically Hindered Secondary Aminoether Alcohols
  申请人：Siskin Michael

  公开号：US20070293705A1

  公开（公告）日：2007-12-20

  Severely sterically hindered secondary aminoether alcohols are prepared by reacting organic carboxylic, organic carboxylic acid halides, acid anhydrides or a ketene with an alkyl, alkaryl or alkylhalo sulfonate to yield a sulfonic-carboxylic anhydride compound which is then reacted with a dioxane to cleave the ring of the dioxane, yielding a cleavage product which cleavage product is then animated with an alkylamine and hydrolyzed with base to yield the severely sterically hindered secondary aminoether alcohol.

  严重的立体位阻次级氨醚醇是通过将有机羧酸、有机羧酸卤化物、酸酐或酮与烷基、烷基芳基或烷基卤代磺酸盐反应制备的，得到磺酸-羧酸酐化合物，然后与二氧六环反应，断开二氧六环的环，得到断裂产物，再与烷基胺动员，并在碱的作用下水解，得到严重的立体位阻次级氨醚醇。
• Zwierzak, Andrzej, Phosphorus, Sulfur and Silicon and the Related Elements, 1993, vol. 75, # 1-4, p. 51 - 54
  作者：Zwierzak, Andrzej

  DOI：——

  日期：——