4,4'-dibromo-3,3'-dimethoxy-2,2'-bithiophene | 1286239-48-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 双噻吩和低聚噻吩
• 英文名称: 4,4'-dibromo-3,3'-dimethoxy-2,2'-bithiophene
• 英文别名: 4-Bromo-2-(4-bromo-3-methoxythiophen-2-yl)-3-methoxythiophene；4-bromo-2-(4-bromo-3-methoxythiophen-2-yl)-3-methoxythiophene
• CAS: 1286239-48-2
• 化学式: C₁₀H₈Br₂O₂S₂
• 分子量: 384.112
• InChiKey: ZPSLXWGHNXXEMW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  74.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-bromo-4-methoxythiophene 在 四丁基氟化铵 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 4.0h， 生成 4,4'-dibromo-3,3'-dimethoxy-2,2'-bithiophene
  参考文献：
  名称：

  3-Alkoxy-4-bromothiophenes: general synthesis of monomers and regio-selective preparation of two dimers

  摘要：

  3-Alkoxy-4-bromothiophenes were synthesized in three steps from the readily available methyl 2-carboxylate-3-hydroxythiophene and two isomers of bithiophenes based on the 3-bromo-4-methoxythiophene moiety were regio-selectively prepared. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.01.050

文献信息

• 3-Alkoxy-4-bromothiophenes: general synthesis of monomers and regio-selective preparation of two dimers
  作者：Gurunathan Savitha、Noémie Hergué、Erwan Guilmet、Magali Allain、Pierre Frère

  DOI：10.1016/j.tetlet.2011.01.050

  日期：2011.3

  3-Alkoxy-4-bromothiophenes were synthesized in three steps from the readily available methyl 2-carboxylate-3-hydroxythiophene and two isomers of bithiophenes based on the 3-bromo-4-methoxythiophene moiety were regio-selectively prepared. (C) 2011 Elsevier Ltd. All rights reserved.