(1,1-Difluoro-2-methylpropyl)cyclohexane

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: (1,1-Difluoro-2-methylpropyl)cyclohexane
• 英文别名: (1,1-difluoro-2-methylpropyl)cyclohexane
• 化学式: C₁₀H₁₈F₂
• 分子量: 176.25
• InChiKey: LTHPXFPZLXJCOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS
  申请人：Frequency Therapeutics, Inc.

  公开号：US20210300948A1

  公开（公告）日：2021-09-30

  The present invention relates to 1H-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.
• [EN] IL-17A MODULATORS AND USES THEREOF<br/>[FR] MODULATEURS D'IL-17A ET LEURS UTILISATIONS
  申请人：DICE ALPHA INC

  公开号：WO2021055376A1

  公开（公告）日：2021-03-25

  The disclosure herein provides compounds and pharmaceutical compositions for the modulation of IL-17A useful for the treatment of inflammatory conditions, such as psoriasis.