2-[(Z)-(4-hydroxy-2-methylphenyl)-(2-methyl-4-oxoniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[(Z)-(4-hydroxy-2-methylphenyl)-(2-methyl-4-oxoniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonate
• 化学式: C21H18O5S
• 分子量: 382.4
• InChiKey: APQRURLENAYZRH-UZYVYHOESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  100
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• pH-MODULATED QUENCHERS OF FLUORESCENCE
  申请人：Berry & Associates, Inc.

  公开号：US20160116448A1

  公开（公告）日：2016-04-28

  The present disclosure relates to a compound of formula (I) or a salt thereof, wherein variable A, B, and X are as defined herein. The disclosure also relates to covalent conjugates of formula (II). The disclosure further relates to the use of the compounds of formula (I) and covalent conjugates of formula (II) in methods for detecting a change in the pH of a mixture.

  本公开涉及公式（I）的化合物或其盐，其中变量A、B和X如本文所定义。该公开还涉及公式（II）的共价结合物。该公开进一步涉及利用公式（I）的化合物和公式（II）的共价结合物来检测混合物中的pH变化的方法。
• Oral care compositions with color changing indicator
  申请人：Sabnis W. Ram

  公开号：US20060222601A1

  公开（公告）日：2006-10-05

  The invention describes color changing toothpastes and mouthwashes which contains acid-base indicator(s) for interaction with the oral cavity to provide a color change indicative of treatment time.

  这项发明描述了含有酸碱指示剂的变色牙膏和漱口水，用于与口腔相互作用，以提供治疗时间的颜色变化指示。
• Organoselenium compounds for cancer chemoprevention
  申请人：LKT Laboratories, Inc.

  公开号：US20020165215A1

  公开（公告）日：2002-11-07

  A compound containing an alkylene selenocyanate or an alkylene isoselenocyanate moiety effective to prevent the occurrence or progression of cancer or a precancerous condition. The compound can be provided and administered in the form of a pharmaceutical composition, a cosmetic, a food additive, supplement, or the like. Methods for synthesis and use of the chemopreventive compound of the invention are also provided.

  一种含有烷基硒氰酸酯或烷基异硒氰酸酯基团的化合物，可有效预防或阻止癌症或癌前病变的发生或进展。该化合物可以以药物组成物、化妆品、食品添加剂、补充剂等形式提供和施用。本发明还提供了合成和使用化学预防化合物的方法。
• Temporary visual indicators for paint and other compositions
  申请人：Simon Leo Patrick

  公开号：US20060008912A1

  公开（公告）日：2006-01-12

  The present invention concerns novel methods and compositions useful for providing a temporary visual indication of the location, concentration, and/or time period of treatment of an applied material. The subject invention provides compositions and methods that use a temporary visual indicator. In certain embodiments, the temporary visual indicator is a pH sensitive visual agent (i.e., dye) that can be added either alone or in combination with other visual agents and/or pH modifying agents. In related embodiments, compositions of the invention comprise a combination of at least one pH modifying agent and at least one pH-sensitive visual agent.

  本发明涉及新颖的方法和组合物，用于提供应用物质的位置、浓度和/或治疗时间段的临时视觉指示。该发明提供了使用临时视觉指示剂的组合物和方法。在某些实施例中，临时视觉指示剂是一种pH敏感的视觉剂（即染料），可以单独或与其他视觉剂和/或pH改性剂组合添加。在相关实施例中，本发明的组合物包括至少一种pH改性剂和至少一种pH敏感的视觉剂的组合。
• Personal care compositions with color changing indicator
  申请人：Sabnis W. Ram

  公开号：US20060222675A1

  公开（公告）日：2006-10-05

  The invention describes a composition for use in disinfecting a surface for personal use, such as a public restroom facility or telephone. The composition and delivery of the composition provides for the placement of a thin layer of disinfectant which includes a acid-base indicator. The acid-base indicator disappears as the thin layer effects the germicidal activity of the disinfectant. The composition is also rapidly drying, so that the acid-base indicator disappears as well as the disinfecting composition leaving the surface dry. The invention also relates to use of the compositions in a lotion, such as a sunscreen. Use of the acid-base indicator provides a method to visualize where the lotion is applied by color, with the color then later dissipating.

  本发明描述了一种用于消毒个人使用表面的组合物，例如公共洗手间或电话。该组合物及其输送方式提供了一层薄薄的消毒剂，其中包括酸碱指示剂。随着薄层发挥消毒剂的杀菌活性，酸碱指示剂消失。该组合物也具有快速干燥的特性，因此酸碱指示剂以及消毒剂在表面干燥后也会消失。本发明还涉及将该组合物用于洗涤剂，例如防晒霜。使用酸碱指示剂提供了一种通过颜色可视化涂抹洗涤剂的方法，颜色随后会消失。