Ethyl 4-[bis(4-fluorophenyl)-hydroxymethyl]piperidine-1-carboxylate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Ethyl 4-[bis(4-fluorophenyl)-hydroxymethyl]piperidine-1-carboxylate
• 化学式: C₂₁H₂₃F₂NO₃
• 分子量: 375.4
• InChiKey: KBJAFKDSDBUFMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] PIPERIDINE COMPOUNDS AND THEIR USE IN THE POPULATION CONTROL OF RODENTS AND OTHER VERTEBRATE PESTS<br/>[FR] COMPOSES DE PIPERIDINE ET LEUR UTILISATION DANS LA LUTTE CONTRE LES POPULATIONS DE RONGEURS ET AUTRES RAVAGEURS VERTEBRES
  申请人：ALMIRALL PRODESFARMA SA

  公开号：WO2000024715A1

  公开（公告）日：2000-05-04

  A piperidine compound of formula (I), wherein R?1 and R2¿ are the same or different and each independently represents an alkyl or C¿3?-C5 cycloalkyl group; R?3¿ represents a hydrogen atom or an alkyl, C¿3?-C5 cycloalkyl, alkanoyl or C3-C5 cycloalkyl-carbonyl group; R?4¿ represents a hydroxy group and R5 represents a hydrogen atom or R?4 and R5¿ together form a covalent bond; X?1 and X2¿ are the same or different and each independently represents a hydrogen or halogen atom; Y?1 and Y2¿ each represents a hydrogen atom or together represent a methylene, ethylene or ethenylene group; except when R?1 and R2¿ are a methyl group, R3 is a hydrogen atom, R4 is a hydroxy group, X?1 and X2¿ are both fluorine atoms and Y?1 and Y2¿ are both hydrogen atoms; and salts thereof; processes for their preparation, compositions containing them and their use in the population control of rodents and other vertebrate pests.