6-(氨基甲基)-(6ci)-嘌呤 | 98141-15-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 中文名称: 6-(氨基甲基)-(6ci)-嘌呤
• 中文别名: (7H-嘌呤-6-基)甲胺
• 英文名称: C-(7(9)H-purin-6-yl)-methylamine
• 英文别名: (7H-Purin-6-YL)methanamine；7H-purin-6-ylmethanamine
• CAS: 98141-15-2
• 化学式: C₆H₇N₅
• mdl: MFCD13189440
• 分子量: 149.155
• InChiKey: FELHYNZKVDMRSU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.166
• 拓扑面积：
  80.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  6-氰嘌呤 在 甲醇 、 钯 作用下， 生成 6-(氨基甲基)-(6ci)-嘌呤
  参考文献：
  名称：

  Synthesis and Properties of Some 6-Substituted Purines¹

  摘要：

  DOI：

  10.1021/ja01548a033

文献信息

• NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT
  申请人：Chen James M.

  公开号：US20100104532A1

  公开（公告）日：2010-04-29

  The invention provides unsaturated phosphonates of Formula I or a tautomer or pharmaceutically accepatble salt thereof, as described herein, as well as pharmaceutical compositions comprising the compounds, and therapeutic methods comprising administering the compounds. The compounds have anti-viral properties and are useful for treating viral infections (e.g. HCV) in animals (e.g. humans).

  本发明提供了公式I或其互变异构体或药学上可接受的盐的不饱和膦酸酯，以及包含这些化合物的制药组合物和包括给予这些化合物的治疗方法。这些化合物具有抗病毒性质，适用于治疗动物（如人类）的病毒感染（例如HCV）。
• A BANK OF STEM CELLS FOR PRODUCING CELLS FOR TRANSPLANTATION HAVING HLA ANTIGENS MATCHING THOSE OF TRANSPLANT RECIPIENTS, AND METHODS FOR MAKING AND USING SUCH A STEM CELL BANK
  申请人：Advanced Cell Technology, Inc.

  公开号：EP1513928A2

  公开（公告）日：2005-03-16
• Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
  申请人：——

  公开号：US20040091936A1

  公开（公告）日：2004-05-13

  Methods for producing stem cell banks, preferably human, which optionally may be transgenic, e.g., comprised of homozygous MHC allele cell lines are provided. These cells are produced preferably from parthenogenic, IVF, or same-species or cross-species nuclear transfer embryos or by de-differentiation of somatic cells by cytoplasm transfer. Methods for using these stem cell banks for producing stem and differentiated cells for therapy, especially acute therapies, and for screening for drugs for disease treatment are also provided.
• BANK OF STEM CELLS FOR PRODUCING CELLS FOR TRANSPLANTATION HAVING HLA ANTIGENS MATCHING THOSE OF TRANSPLANT RECIPIENTS AND METHODS FOR MAKING AND USING SUCH A STEM CELL BANK
  申请人：Advanced Cell Technology, Inc.

  公开号：US20190225937A1

  公开（公告）日：2019-07-25

  Methods for producing stem cell banks, preferably human, which optionally may be transgenic, e.g., comprised of homozygous MHC allele cell lines are provided. These cells are produced preferably from parthenogenic, IVF, or same-species or cross-species nuclear transfer embryos or by de-differentiation of somatic cells by cytoplasm transfer. Methods for using these stem cell banks for producing stem and differentiated cells for therapy, especially acute therapies, and for screening for drugs for disease treatment are also provided.
• US8324179B2
  申请人：——

  公开号：US8324179B2

  公开（公告）日：2012-12-04