Piperidine salt of 2,4-thiazolidinedione | 74008-05-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: Piperidine salt of 2,4-thiazolidinedione
• 英文别名: piperidine;1,3-thiazolidine-2,4-dione
• CAS: 74008-05-2
• 化学式: C8H14N2O2S
• 分子量: 202.28
• InChiKey: ATHWHSAQWLJMQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.73
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  83.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• NOVEL HETEROCYCLIC ANALOGS OF DIPHENYLETHYLENE COMPOUNDS
  申请人：Theracos, Inc.

  公开号：EP1549625A1

  公开（公告）日：2005-07-06
• SCD1 ANTAGONISTS FOR TREATING CANCER
  申请人：F.Hoffmann-La Roche AG

  公开号：EP2766000A2

  公开（公告）日：2014-08-20
• METHODS OF USING SCD1 ANTAGONISTS
  申请人：Genentech, Inc.

  公开号：US20130096181A1

  公开（公告）日：2013-04-18

  Provided herein are therapies for the treatment of pathological conditions, such as cancer, and method of using SCD1 antagonists.
• US9358250B2
  申请人：——

  公开号：US9358250B2

  公开（公告）日：2016-06-07
• [EN] NOVEL HETEROCYCLIC ANALOGS OF DIPHENYLETHYLENE COMPOUNDS<br/>[FR] NOUVEAUX ANALOGUES HETEROCYCLIQUES DE COMPOSES DE DIPHENYLETHYLENE
  申请人：THERACOS INC

  公开号：WO2004033438A1

  公开（公告）日：2004-04-22

  Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.