1-(2,4-dichlorophenyl)-3-(1,2-oxazol-5-yl)urea | 263385-47-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2,4-dichlorophenyl)-3-(1,2-oxazol-5-yl)urea
• CAS: 263385-47-3
• 化学式: C₁₀H₇Cl₂N₃O₂
• 分子量: 272.09
• InChiKey: DDEFDHBAPLUCLF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  67.2
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] COMPOUNDS, COMPOSITIONS, AND METHODS FOR INHIBITING BACTERIAL GROWTH<br/>[FR] COMPOSÉS, COMPOSITIONS ET PROCÉDÉS POUR L'INHIBITION DE LA CROISSANCE BACTÉRIENNE
  申请人：UNIV MICHIGAN STATE

  公开号：WO2018067769A1

  公开（公告）日：2018-04-12

  The present disclosure provides, among other things, compounds, compositions, and methods useful for inhibiting bacteria, such as Mycobacterium tuberculosis. These compositions and methods find many uses in medicine and research, e.g., treating subjects afflicted with active or latent bacterial infections.

  本公开提供了一些化合物、组合物和方法，用于抑制细菌，如结核分枝杆菌。这些组合物和方法在医学和研究中有许多用途，例如治疗患有活动或潜在细菌感染的受试者。
• UREA DERIVATIVES AS ABL MODULATORS
  申请人：Grotzfeld Robert M.

  公开号：US20100173917A1

  公开（公告）日：2010-07-08

  The invention provides methods and compositions for treating conditions mediated by Bcr-Abl. The invention also provides methods of using the compounds and/or compositions in the treatment of a variety of diseases and unwanted conditions in subjects.

  本发明提供了治疗由Bcr-Abl介导的疾病的方法和组合物。本发明还提供了使用这些化合物和/或组合物治疗受试者的各种疾病和不良情况的方法。
• COMPOUNDS, COMPOSITIONS, AND METHODS FOR INHIBITING BACTERIAL GROWTH
  申请人：Board of Trustees of Michigan Stat University

  公开号：US20200046678A1

  公开（公告）日：2020-02-13

  The present disclosure provides, among other things, compounds, compositions, and methods useful in inhibiting bacteria, such as Mycobacterium tuberculosis . These compositions and methods find many uses in medicine and research, e.g., treating subjects afflicted with active or latent bacterial infections.
• CHEMICAL INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS DOSRST SIGNALING AND PERSISTENCE
  申请人：Board of Trustees of Michigan State University

  公开号：US20210000799A1

  公开（公告）日：2021-01-07

  Provides herein are novel compounds, compositions, and methods useful for inhibiting bacteria, such as Mycobacterium tuberculosis . These compositions and methods find many uses in medicine and research, e.g., treating subjects afflicted with active or latent bacterial infections.
• US7750160B2
  申请人：——

  公开号：US7750160B2

  公开（公告）日：2010-07-06