[2-[(4-Azidophenyl)methyl]-4-nitrophenyl] hydrogen carbonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [2-[(4-Azidophenyl)methyl]-4-nitrophenyl] hydrogen carbonate
• 英文别名: [2-[(4-azidophenyl)methyl]-4-nitrophenyl] hydrogen carbonate
• 化学式: C14H10N4O5
• 分子量: 314.25
• InChiKey: OKHCGNDYUZNNDM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  107
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Detection Assays and Use Thereof
  申请人：Haff Lawrence A.

  公开号：US20100159446A1

  公开（公告）日：2010-06-24

  The invention provides compositions and methods for the detection and/or quantification of biological targets (e.g., nucleic acids and proteins) by the nucleic acid-templated creation of one or more reaction products, for example, epitopes, enzyme substrates, enzyme activators, and ligands. The reaction products can be detected and/or quantitated after signal amplification using an amplification system.

  本发明提供了一种通过核酸模板创建一个或多个反应产物（例如表位、酶底物、酶活化剂和配体）来检测和/或定量生物靶标（例如核酸和蛋白质）的组合物和方法。在使用放大系统进行信号放大后，可以检测和/或定量反应产物。
• PEPTIDE-COMPOUND CYCLIZATION METHOD
  申请人：Chugai Seiyaku Kabushiki Kaisha

  公开号：US20150080549A1

  公开（公告）日：2015-03-19

  An object of the present invention is to provide methods of discovering drugs effective for tough targets, which have conventionally been discovered only with difficulty. The present invention relates to novel methods for cyclizing peptide compounds, and novel peptide compounds and libraries comprising the same, to achieve the above object.

  本发明的目的是提供一种发现对于难以处理的靶点有效的药物的方法，这些药物通常很难被发现。本发明涉及新型的环化肽化合物的方法，以及包含这些化合物的新型肽库，以实现上述目的。
• DETECTION ASSAYS AND USE THEREOF
  申请人：Ensemble Discovery Corporation

  公开号：EP2191268A2

  公开（公告）日：2010-06-02
• US9409952B2
  申请人：——

  公开号：US9409952B2

  公开（公告）日：2016-08-09
• [EN] DETECTION ASSAYS AND USE THEREOF<br/>[FR] ANALYSES DE DÉTECTION ET UTILISATION DE CELLES-CI
  申请人：ENSEMBLE DISCOVERY CORP

  公开号：WO2009018003A2

  公开（公告）日：2009-02-05

  The invention provides compositions and methods for the detection and/or quantification of biological targets (e.g., nucleic acids and proteins) by the nucleic acid-templated creation of one or more reaction products, for example, epitopes, enzyme substrates, enzyme activators, and ligands. The reaction products can be detected and/or quantitated after signal amplification using an amplification system.