Bis(4-nitrophenyl) but-2-enedioate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: Bis(4-nitrophenyl) but-2-enedioate
• 化学式: C16H10N2O8
• 分子量: 358.26
• InChiKey: ZLNCGIAXVWNFRX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  144
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• BIS-( -AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE
  申请人：Medivas, LLC

  公开号：EP1926780A2

  公开（公告）日：2008-06-04
• AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE
  申请人：Medivas, LLC

  公开号：EP1948203A2

  公开（公告）日：2008-07-30
• ALKYLENE-DICARBOXYLATE-CONTAINING BIODEGRADABLE POLY(ESTER AMIDES) AND METHODS OF USE
  申请人：Medivas, LLC

  公开号：EP2004145A2

  公开（公告）日：2008-12-24
• Aromatic di-acid-containing poly (ester amide) polymers and methods of use
  申请人：Gomurashvili D. Zaza

  公开号：US20070106035A1

  公开（公告）日：2007-05-10

  The present invention provides biodegrable, biocompatible aromatic di-acid-containing poly(ester amide) (PEA) polymers with thermo-mechanical properties that can be readily tailored by selection of various combinations and proportions of the di-acid residues in the polymers. The polymers are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The polymer compositions and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.
• BIS-(ALPHA-AMINO)-DIOL-DIESTER-CONTAINING POLY (ESTER AMIDE) AND POLY (ESTER URETHANE) COMPOSITIONS AND METHODS OF USE
  申请人：MEDIVAS, LLC

  公开号：US20130210931A1

  公开（公告）日：2013-08-15

  The present invention provides biodegradable, biocompatible bis-(α-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.