(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-(2-hydroxyphenyl)acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-(2-hydroxyphenyl)acetamide
• 化学式: C₁₃H₁₅F₂NO₂
• 分子量: 255.26
• InChiKey: RKBRRZYCOQIZIO-LDYMZIIASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  63.3
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] N-ARALKYLCARBONYL-PIPERAZINE AND -HOMOPIPERAZINE COMPOUNDS AND PERSONAL CARE COMPOSITIONS COMPRISING THE SAME<br/>[FR] COMPOSÉS DE N-ARALKYLCARBONYLE-PIPÉRAZINE ET N-ARALKYLCARBONYLE-HOMOPIPÉRAZINE ET COMPOSITIONS DE SOINS PERSONNELS LES COMPRENANT
  申请人：UNILEVER PLC

  公开号：WO2016173817A1

  公开（公告）日：2016-11-03

  A personal care composition comprising N-aralkylcarbonyl-piperazine and/or - homopiperazines. When such compounds are used in personal care compositions, they have been unexpectedly to enhance cell proliferation and epidermal thickness, traits associated with younger, healthy looking skin.

  一种包含N-芳基羰基哌嗪和/或-N-同源哌嗪的个人护理组合物。当这些化合物用于个人护理组合物中时，它们被意外地发现可以促进细胞增殖和表皮厚度增加，这些特征与年轻、健康肌肤有关。
• N-aralkylcarbonyl-piperazine and -homopiperazine compounds and personal care compositions comprising the same
  申请人：Conopco, Inc.

  公开号：US10155733B2

  公开（公告）日：2018-12-18

  A personal care composition comprising N-aralkylcarbonyl-piperazine and/or -homopiperazines. When such compounds are used in personal care compositions, they have been unexpectedly to enhance cell proliferation and epidermal thickness, traits associated with younger, healthy looking skin.

  一种含有 N-烷基羰基哌嗪和/或高哌嗪的个人护理组合物。当这类化合物用于个人护理组合物中时，它们会出人意料地增强细胞增殖和表皮厚度，这些特征都与年轻、健康的皮肤有关。
• N-ARALKYLCARBONYL-PIPERAZINE AND -HOMOPIPERAZINE COMPOUNDS AND PERSONAL CARE COMPOSITIONS COMPRISING THE SAME
  申请人：Unilever PLC

  公开号：EP3288926B1

  公开（公告）日：2021-01-20