申请人:MEI PHARMA, INC.
公开号:US10201527B2
公开(公告)日:2019-02-12
The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
本发明涉及作为组蛋白去乙酰化酶抑制剂的羟酰胺化合物。更具体地说,本发明涉及含苯并咪唑的化合物及其制备方法。这些化合物可用作治疗增殖性疾病以及涉及组蛋白去乙酰化酶(HDAC)失调或与之有关的其他疾病的药物。