5-(2-Azidoethyl)-10-phenylmethoxy-4,5,8,10-tetrazatricyclo[6.2.1.02,6]undeca-2(6),3-dien-9-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 5-(2-Azidoethyl)-10-phenylmethoxy-4,5,8,10-tetrazatricyclo[6.2.1.02,6]undeca-2(6),3-dien-9-one
• 英文别名: 5-(2-azidoethyl)-10-phenylmethoxy-4,5,8,10-tetrazatricyclo[6.2.1.02,6]undeca-2(6),3-dien-9-one
• 化学式: C16H17N7O2
• 分子量: 339.35
• InChiKey: MARADNWNPGTAGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  65
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Novel heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
  申请人：AVENTIS PHARMA S.A.

  公开号：US20040157826A1

  公开（公告）日：2004-08-12

  The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: 1 The invention also relates to a method for preparing these compounds, and to their use as medicaments, in particular as antibacterials and &bgr;-lactamase inhibitors.

  这项发明涉及一般式(I)的新异环化合物及其与碱或酸的盐：1。该发明还涉及制备这些化合物的方法，并将它们用作药物，特别是作为抗菌药物和β-内酰胺酶抑制剂。
• NOVEL HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTIBACTERIALS AND BETA-LACTAMASE INHIBITORS
  申请人：Lampilas Maxime

  公开号：US20090018329A1

  公开（公告）日：2009-01-15

  The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a method for preparing these compounds, and to their use as medicaments, in particular as antibacterials and β-lactamase inhibitors.

  该发明涉及一种新型杂环化合物，其通式为（I），以及它们与酸或碱的盐：该发明还涉及一种制备这些化合物的方法，并将其用作药物，特别是作为抗菌剂和β-内酰胺酶抑制剂。
• COMPOSES HETEROCYCLIQUES, LEUR PREPARATION ET LEUR UTILISATION COMME MEDICAMENTS, NOTAMMENT COMME ANTI-BACTERIENS ET INHIBITEURS DE BETA-LACTAMASES
  申请人：NOVEXEL

  公开号：EP1569935B1

  公开（公告）日：2008-08-20
• US7439253B2
  申请人：——

  公开号：US7439253B2

  公开（公告）日：2008-10-21