2-Fluoro-6-[4-(methylsulfonimidoyl)phenoxy]benzonitrile

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Fluoro-6-[4-(methylsulfonimidoyl)phenoxy]benzonitrile
• 化学式: C₁₄H₁₁FN₂O₂S
• 分子量: 290.31
• InChiKey: DFZZDATYDOFVGL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  82.3
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides
  申请人：——

  公开号：US20020032328A1

  公开（公告）日：2002-03-14

  Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides Acylsulfimides of the formula (I) 1 where the symbols and indices are as defined in the description, are suitable for controlling animal pests.

  含杂环的酰基磺酰亚胺，其制备方法，包含它们的组合物以及它们作为杀虫剂的用途。式(I)中符号和指数如描述中定义的酰基磺酰亚胺，适用于控制动物害虫。
• Method for producing 4-haloalkyl nicotinic acid amides
  申请人：Pazenok Sergiy

  公开号：US20050176734A1

  公开（公告）日：2005-08-11

  The invention relates to a method for producing 4-haloalkylnicotinamides having the formula (I): wherein R 1 is (C 1 -C 4 )haloalky, comprising subjecting one or more 3-((C 1 -C 4 )haloalkyl-3-oxo-1-alkenylamino)nitriles of the formula (II), (III) or (IV): R 1 —C(O)—CH═CH—NH—CH═CH—CN   (II) R 1 —C(O)—CH═CH—NH—CH(ZR 2 )—CH 2 —CN   (III) R 1 —C(O)—CH═CH—NH—CH(Hal)-CH 2 —CN   (IV) where R 1 is as defined above, R 2 is the same or different and is (C 1 -C 6 )-alkyl and Z is the same or different and is O, S or NR 1 , to a ring-closing reaction and simultaneous hydrolysis in the presence of a strong acid.

  本发明涉及一种制备式（I）的4-卤代烷基烟酰胺的方法，其中R1为（C1-C4）卤代烷基，包括将一个或多个式（II）、（III）或（IV）的3-（（C1-C4）卤代烷基-3-氧代-1-烯基氨基）腈置于强酸存在下进行环合反应和同时水解，其中R1如上所定义，R2相同或不同且为（C1-C6）烷基，Z相同或不同且为O、S或NR1：R1—C（O）—CH═CH—NH—CH═CH—CN（II）；R1—C（O）—CH═CH—NH—CH（ZR2）—CH2—CN（III）；R1—C（O）—CH═CH—NH—CH（Hal）- —CN（IV）。