2-Fluoroheptadecane

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: 2-Fluoroheptadecane
• 英文别名: 2-fluoroheptadecane
• 化学式: C₁₇H₃₅F
• 分子量: 258.5
• InChiKey: KBBFBNSNNMMKRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  18
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] PLASMALOGEN DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS DE PLASMALOGÈNES ET LEURS UTILISATIONS
  申请人：[en]PHOSKA BIOPHARMA PTE. LTD.

  公开号：WO2022263927A2

  公开（公告）日：2022-12-22

  Provided herein are compounds (e.g., compounds of Formulae (I) and (II)), and pharmaceutically acceptable salts, hydrates, solvates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof, and compositions, methods, uses, and kits thereof. The compounds provided herein include plasmalogens and plasmalogen derivatives. The compounds provided herein may cross the blood-brain barrier and/or blood-retinal barrier or be transported by the Mfsd2a protein. Accordingly, such compounds are useful for the treatment and/or prevention of various diseases and conditions (e.g., liver diseases, neurological diseases, ophthalmic diseases, metabolic disorders, mitochondrial diseases, cardiovascular diseases, infectious diseases, pulmonary diseases, skin diseases, genetic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, hematological diseases, painful conditions, psychiatric disorders, immune disorders, and spleen diseases).