N-(4-nitrophenyl)-9-oxofluorene-1-carboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-nitrophenyl)-9-oxofluorene-1-carboxamide
• 化学式: C20H12N2O4
• mdl: MFCD00998931
• 分子量: 344.3
• InChiKey: YTLJRPWXDOIRJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  92
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Methods and Compositions to Inhibit Edema Factor and Adenylyl Cyclase
  申请人：Schein Catherine H.

  公开号：US20090093519A1

  公开（公告）日：2009-04-09

  Small molecules and their derivatives are described for the treatment and/or prevention of intestinal fluid loss. Also disclosed are methods of using said molecules and their derivatives to treat and/or prevent conditions associated with increased levels of 3′,5′-adenosine monophosphate. Specific compositions of the invention are also novel.

  本发明描述了用于治疗和/或预防肠道液体丢失的小分子及其衍生物。还公开了使用所述分子及其衍生物治疗和/或预防与3′，5′-腺苷酸单磷酸增加水平相关的疾病的方法。本发明的特定组合物也是新颖的。
• METHODS AND COMPOSITIONS TO INHIBIT EDEMA FACTOR AND ADENYLYL CYCLASE
  申请人：Schein Catherine H.

  公开号：US20120010233A1

  公开（公告）日：2012-01-12

  Small molecules and their derivatives are described for the treatment and/or prevention of intestinal fluid loss. Also disclosed are methods of using said molecules and their derivatives to treat and/or prevent conditions associated with increased levels of 3′,5′-adenosine monophosphate. Specific compositions of the invention are also novel.

  本发明涉及用于治疗和/或预防肠道液体流失的小分子及其衍生物。还公开了使用所述分子及其衍生物治疗和/或预防与3′，5′-腺苷酸单磷酸酯水平增加相关的疾病的方法。本发明的特定组合物也是新颖的。
• US8003692B2
  申请人：——

  公开号：US8003692B2

  公开（公告）日：2011-08-23