3-Heptan-4-ylpyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-Heptan-4-ylpyridine
• 英文别名: 3-heptan-4-ylpyridine
• 化学式: C₁₂H₁₉N
• 分子量: 177.29
• InChiKey: CWHCGJPEEWTXNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• TRISUBSTITUTED PYRIDO[2,3-D]PYRIMIDINES, METHODS FOR PREPARING SAME AND THERAPEUTIC USES THEREOF
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)

  公开号：US20150203489A1

  公开（公告）日：2015-07-23

  The present invention relates to compounds of the following general formula (I): wherein: R 1 is notably a group —NR a R b , R a and R b forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R 2 is notably an aryl comprising from 5 to 30 atoms, and R 3 is notably an alkenyl comprising from 1 to 20 carbon atoms.

  本发明涉及以下通式(I)的化合物： 其中： R1特别地是一个基团—NRaRb，Ra和Rb与它们所连接的氮原子一起形成一个包含5至30个原子的杂环； R2特别地是一个包含5至30个原子的芳基； R3特别地是一个包含1至20个碳原子的烯基。
• Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)

  公开号：US10202372B2

  公开（公告）日：2019-02-12

  The present invention relates to compounds of the following general formula (I): wherein: R1 is notably a group —NRaRb, Ra and Rb forming together with the nitrogen atom onto which they are bound, a heterocycle comprising from 5 to 30 atoms, R2 is notably an aryl comprising from 5 to 30 atoms, and R3 is notably an alkenyl comprising from 1 to 20 carbon atoms.

  本发明涉及以下一般式（I）的化合物：其中：R1 明显是一个基团—NRaRb，Ra 和 Rb 与它们结合的氮原子一起形成一个含有 5 到 30 个原子的杂环，R2 明显是一个含有 5 到 30 个原子的芳基，R3 明显是一个含有 1 到 20 个碳原子的烯基。
• Imidazo[2,1-f][1,2,4]triazine compounds as pi3k-y inhibitors
  申请人：Incyte Corporation

  公开号：US10975088B2

  公开（公告）日：2021-04-13

  This application relates to compounds of Formula (I): or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of PI3K-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.

  本申请涉及式 (I) 化合物： 或其药学上可接受的盐或立体异构体，它们是 PI3K-γ 的抑制剂，可用于治疗自身免疫性疾病、癌症、心血管疾病和神经退行性疾病等疾病。