1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine)--hydrogen bromide (1/2) | 64690-20-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine)--hydrogen bromide (1/2)
• 英文别名: N-octyl-1-[10-(4-octyliminopyridin-1-yl)decyl]pyridin-4-imine;dihydrobromide
• CAS: 64690-20-6
• 化学式: C36H64Br2N4
• 分子量: 712.7
• InChiKey: UVKYQBWVUOZNSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.64
• 重原子数：
  42
• 可旋转键数：
  27
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  31.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] OCTENIDINE BASED COMPOUNDS<br/>[FR] COMPOSÉS À BASE D'OCTÉNIDINE
  申请人：DISHMAN CARBOGEN AMCIS LTD

  公开号：WO2019038669A1

  公开（公告）日：2019-02-28

  The present invention discloses Octenidine based compounds of formula (A) or formula (B) and formula(C) where in, n=1,2,3,4 and R'=un-substituted or substituted aryl or alkyl group; R is hydroxy or hydrogen, X is chlorine, bromine and iodine. The present invention also relates to a process for the preparation thereof.

  本发明披露了基于八亚甲基-4,5-二氮杂-2-丙醇（Octenidine）的化合物，其化学式为（A）或（B）和（C），其中n=1,2,3,4，R'=未取代或取代的芳基或烷基；R为羟基或氢，X为氯、溴和碘。本发明还涉及一种制备该化合物的方法。
• COMPOSITION COMPRISING AN ANTISEPTIC, A VOLATILE SULFUR COMPOUND NEUTRALIZER, AND AN ANTICARIOGENIC AGENT
  申请人：Lacer, S.A.

  公开号：EP3421029A1

  公开（公告）日：2019-01-02

  It relates to a buccal composition which comprises an effective amount of octenidine or a pharmaceutically, veterinary or cosmetically acceptable salt thereof, a zinc ion source, and fluoride ion source, together with one or more appropriate oral excipients or carriers. It also relates to a process for its preparation and to its medical uses in the treatment of halitosis, prophylaxis and/or treatment of periodontal diseases, and prophylaxis of dental caries. It also relates to its cosmetic use as an oral care agent.

  它涉及一种口腔组合物，其中包含有效量的辛烯胺或其药用、兽用或化妆品可接受的盐、锌离子源和氟离子源，以及一种或多种适当的口腔赋形剂或载体。本发明还涉及其制备工艺及其在治疗口臭、预防和/或治疗牙周疾病以及预防龋齿方面的医疗用途。还涉及其作为口腔护理剂的美容用途。
• Octendidine based compounds
  申请人：DISHMAN CARBOGEN AMCIS LTD.

  公开号：US11014907B2

  公开（公告）日：2021-05-25

  The present invention discloses Octenidine based compounds of formula (A) or formula (B) and formula (C) where in, n=1, 2, 3, 4 and R′=un-substituted or substituted aryl or alkyl group; R is hydroxy or hydrogen, X is chlorine, bromine and iodine. The present invention also relates to a process for the preparation thereof.

  本发明公开了式(A)或式(B)和式(C)的辛烯胺基化合物，其中，n＝1、2、3、4，R′＝未取代或取代的芳基或烷基；R为羟基或氢，X为氯、溴和碘。本发明还涉及其制备工艺。
• OCTENIDINE BASED COMPOUNDS
  申请人：Dishman Carbogen Amcis Ltd.

  公开号：EP3672942A1

  公开（公告）日：2020-07-01
• OCTENDIDINE BASED COMPOUNDS
  申请人：DISHMAN CARBOGEN AMCIS LTD.

  公开号：US20200377471A1

  公开（公告）日：2020-12-03

  The present invention discloses Octenidine based compounds of formula (A) or formula (B) and formula (C) where in, n=1,2,3,4 and R′=un-substituted or substituted aryl or alkyl group; R is hydroxy or hydrogen, X is chlorine, bromine and iodine. The present invention also relates to a process for the preparation thereof.