N-[5-[2-(2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide;hydrobromide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[5-[2-(2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide;hydrobromide
• 化学式: C21H19BrN4O2S2
• 分子量: 503.4
• InChiKey: SRZQYTPACFNBMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.16
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  133
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• CELL LINES EXPRESSING CFTR AND METHODS OF USING THEM
  申请人：Shekdar Kambiz

  公开号：US20120058918A1

  公开（公告）日：2012-03-08

  Disclosed herein are cells and cell lines that stably express CFTR and methods for using those cells and cell lines. The invention also includes techniques for creating these cells and cell lines. The cells and cell lines of this invention are physiologically relevant. They are highly sensitive and provide consistent and reliable results in cell-based assays.
• [EN] CELL LINES EXPRESSING CFTR AND METHODS OF USING THEM<br/>[FR] LIGNÉES CELLULAIRES EXPRIMANT CFTR ET PROCÉDÉS D'UTILISATION ASSOCIÉS
  申请人：CHROMOCELL CORP

  公开号：WO2010088630A2

  公开（公告）日：2010-08-05

  Disclosed herein are cells and cell lines that stably express CFTR and methods for using those cells and cell lines. The invention also includes techniques for creating these cells and cell lines. The cells and cell lines of this invention are physiologically relevant. They are highly sensitive and provide consistent and reliable results in cell-based assays.