N-[(5-chloro-8-hydroxyquinolin-7-yl)-(2,4-dichlorophenyl)methyl]-4-methoxybenzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[(5-chloro-8-hydroxyquinolin-7-yl)-(2,4-dichlorophenyl)methyl]-4-methoxybenzamide
• 化学式: C₂₄H₁₇Cl₃N₂O₃
• 分子量: 487.8
• InChiKey: QVNAHIYRPRUQQY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  71.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] COMPOSITIONS AND METHODS FOR TREATING CRYPTOSPORIDIOSIS<br/>[FR] COMPOSITIONS ET MÉTHODES DE TRAITEMENT DE LA CRYPTOSPORIDIOSE
  申请人：UNIV VERMONT

  公开号：WO2015073836A1

  公开（公告）日：2015-05-21

  Methods for treating or prophylaxis of a Cryptosporidium infection using compositions comprising a structure disclosed herein. Also provided are pharmaceutical compositions and kits for alleviating the symptoms of, for treating, or for preventing the occurrence of Cryptosporidium infection. The kits comprise one or more compounds having a structure disclosed herein, such as in an oral composition, and instructions for use, storage, and the like.