[4-(2-Iminoacetyl)phenyl] acetate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: [4-(2-Iminoacetyl)phenyl] acetate
• 英文别名: [4-(2-iminoacetyl)phenyl] acetate
• 化学式: C₁₀H₉NO₃
• 分子量: 191.18
• InChiKey: WLGQHZRGCGMVFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  67.2
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• METHOD FOR PREPARING PERFLUOROALKYL SULFINATE ESTER
  申请人：SOOCHOW UNIVERSITY

  公开号：US20210221769A1

  公开（公告）日：2021-07-22

  The present invention discloses a method for preparing a perfluoroalkyl sulfinate ester. The method includes reacting an α-carbonyldiazo compound and a sodium perfluoroalkyl sulfinate, in an organic solvent, in the presence of anhydrous copper acetate as an optimal catalyst and tert-butyl hydroperoxide (TBHP) as a green oxidant, to obtain the perfluoroalkyl sulfinate ester. Compared to the prior art, the present method has the advantages of a wide range of reaction substrates, a short reaction time, a high reaction yield, and mild reaction conditions. The reaction does not require pre-activation of sodium perfluoroalkyl sulfinate, which can participate in the reaction directly, making reaction operations simple. The present method uses TBHP as a green oxidant and produces tert-butanol and water after reaction. Moreover, the present method avoids using a bromide or a chloride as a reaction material, and thus avoids formation of a large amount of a halide salt.

  本发明公开了一种制备全氟烷基磺酸酯的方法。该方法包括在有机溶剂中，通过在无水乙酸铜存在下，将α-羰基重氮化合物和全氟烷基磺酸钠反应，以叔丁基过氧化氢（TBHP）作为绿色氧化剂，获得全氟烷基磺酸酯。与现有技术相比，本方法具有反应底物范围广，反应时间短，反应产率高，反应条件温和等优点。该反应不需要对全氟烷基磺酸钠进行预激活，它可以直接参与反应，使得反应操作简单。本方法使用TBHP作为绿色氧化剂，在反应后产生叔丁醇和水。此外，本方法避免使用溴化物或氯化物作为反应物质，因此避免了大量卤化物盐的形成。