2-Hexylamino-1-(4-isopropylsulfanyl-phenyl)-propan-1-ol | 54767-65-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Hexylamino-1-(4-isopropylsulfanyl-phenyl)-propan-1-ol
• 英文别名: alpha-(1-(Hexylamino)ethyl)-4-((1-methylethyl)thio)benzenemethanol；2-(hexylamino)-1-(4-propan-2-ylsulfanylphenyl)propan-1-ol
• CAS: 54767-65-6
• 化学式: C₁₈H₃₁NOS
• 分子量: 309.516
• InChiKey: SKRMSEQRBCTDLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  57.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES
  申请人：Washington University

  公开号：US20210228591A1

  公开（公告）日：2021-07-29

  The present disclosure relates generally compositions and methods of using the same for the treatment of proteinopathies (e.g. Alpha-1-antitrypsin deficiency, Non-alcoholic fatty liver disease, Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, and Huntington's disease) with one or more proteotoxicity reducing agents.
• [EN] COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES<br/>[FR] COMPOSITIONS ET PROCÉDÉS D'UTILISATION DE CELLES-CI POUR LE TRAITEMENT DE PROTÉINOPATHIES
  申请人：UNIV WASHINGTON

  公开号：WO2019204764A1

  公开（公告）日：2019-10-24

  The present disclosure relates generally compositions and methods of using the same for the treatment of proteinopathies (e.g. Alpha-1-antitrypsin deficiency, Non-alcoholic fatty liver disease, Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, and Huntington's disease) with one or more proteotoxicity reducing agents.