2-Cyclopentyl-2-hydroxy-2-phenylacetaldehyd | 31142-50-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Cyclopentyl-2-hydroxy-2-phenylacetaldehyd
• 英文别名: 2-Cyclopentyl-2-hydroxy-2-phenylacetaldehyde；2-cyclopentyl-2-hydroxy-2-phenylacetaldehyde
• CAS: 31142-50-4
• 化学式: C₁₃H₁₆O₂
• 分子量: 204.269
• InChiKey: OJRCNZGGFXQNAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] NEBULIZATION COMPOSITION COMPRISING GLYCOPYRROLATE AND ARFORMOTEROL<br/>[FR] COMPOSITION DE NÉBULISATION COMPRENANT DU GLYCOPYRROLATE ET DE L'ARFORMOTÉROL
  申请人：GLENMARK SPECIALTY SA

  公开号：WO2020148638A1

  公开（公告）日：2020-07-23

  The present invention relates to a nebulization composition comprising glycopyrrolate and arformoterol for the treatment of inflammatory or obstructive airway disease and a process for preparing the composition.
• [EN] CRYSTALLINE FORM OF SOFPIRONIUM BROMIDE AND PREPARATION METHOD THEREOF<br/>[FR] FORME CRISTALLINE DE BROMURE DE SOFPIRONIUM ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
  申请人：KAKEN PHARMA CO LTD

  公开号：WO2020235665A1

  公开（公告）日：2020-11-26

  A cocrystal containing the 1'R-diastereomer and the 1'S-diastereomer of sofpironium bromide at a ratio of 1:3 (Form CO), a crystal mixture (for example, Form B) containing Form CO and a crystalline form of the 1'R-diastereomer (Form MN), and a method for preparing sofpironium bromide, which is suitable for manufacture of the crystal mixture are provided. Form CO and a crystalline form of sofpironium bromide containing Form CO (for example, Form B) have superior stability without hygroscopic property, and accordingly they can be preferably used as a raw material of medicaments.