2-Benzylidenepyrrolidine | 258881-90-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Benzylidenepyrrolidine
• CAS: 258881-90-2
• 化学式: C₁₁H₁₃N
• 分子量: 159.231
• InChiKey: AGIBHTHSMHAQEM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  5-苯基戊-4-炔-1-胺 在 Yb-1,10-phenanthroline complex 作用下， 生成 2-Benzylidenepyrrolidine
  参考文献：
  名称：

  Intramolecular Hydroamination of Aminoalkynes with Silver−Phenanthroline Catalysts

  摘要：

  Intramolecular hydroamination of several aminoalkynes catalyzed by silver-phenanthroline complexes is reported. This catalyst system complements previous protocols by employing air- and moisture-stable complexes without compromising activity or reaction control. Some of the hydroamination products are subject to a useful aerobic oxidation. Silver-phenanthroline complexes have successfully demonstrated efficacy in the desymmetrization of a prochiral diyne.

  DOI：

  10.1021/ol801458g

文献信息

• Zinc–zinc bonded decamethyldizincocene Zn2(η5-C5Me5)2 as catalyst for the inter- and intramolecular hydroamination reaction
  作者：Anja Lühl、Hari Pada Nayek、Siegfried Blechert、Peter W. Roesky

  DOI：10.1039/c1cc12461g

  日期：——

  The Zn–Zn bonded compound [(η5-Cp*)2Zn2] was investigated as catalyst for the inter- and intramolecular hydroamination reaction. High reaction rates under mild conditions were observed. This is the first application of a Zn–Zn bonded compound as catalyst.

  研究了锌-锌键化合物[(η5-Cp*)2Zn2]作为催化剂在分子间和分子内氨化反应中的应用，结果显示在温和条件下具有较高的反应速率。这是首次将锌-锌键化合物作为催化剂的应用。
• Intramolecular Hydroamination of Aminoalkynes with Silver−Phenanthroline Catalysts
  作者：Jeffrey M. Carney、Patrick J. Donoghue、William M. Wuest、Olaf Wiest、Paul Helquist

  DOI：10.1021/ol801458g

  日期：2008.9.1

  Intramolecular hydroamination of several aminoalkynes catalyzed by silver-phenanthroline complexes is reported. This catalyst system complements previous protocols by employing air- and moisture-stable complexes without compromising activity or reaction control. Some of the hydroamination products are subject to a useful aerobic oxidation. Silver-phenanthroline complexes have successfully demonstrated efficacy in the desymmetrization of a prochiral diyne.