N-methoxy-N-(1-methylpiperidin-4-yl)benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-methoxy-N-(1-methylpiperidin-4-yl)benzamide
• 化学式: C₁₄H₂₀N₂O₂
• 分子量: 248.32
• InChiKey: BBRBZBJVWUQBDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  32.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• COMPOSITIONS AND METHODS FOR IMPROVING INDUCED NEURON GENERATION
  申请人：PRESIDENT AND FELLOWS OF HARVARD COLLEGE

  公开号：US20160115447A1

  公开（公告）日：2016-04-28

  The present inventions relate to methods and compositions useful for improving the efficiency of inducing the generation of neurons from non-neuronal cell types, for example, by contacting the cell or cell culture medium with one or more agents which inhibit Activin and/or PLK1 signaling. Also disclosed are methods for promoting neuron survival, for example, by inhibiting Activin and/or PLK1 signaling, and methods for promoting the survival of intermediates in a cell differentiation pathway, for example, by inhibiting Activin and/or PLK1 signaling.
• [EN] COMPOSITIONS AND METHODS FOR IMPROVING INDUCED NEURON GENERATION<br/>[FR] COMPOSITIONS ET PROCÉDÉS PERMETTANT D'AMÉLIORER LA PRODUCTION INDUITE DE NEURONES
  申请人：HARVARD COLLEGE

  公开号：WO2014201133A1

  公开（公告）日：2014-12-18

  The present inventions relate to methods and compositions useful for improving the efficiency of inducing the generation of neurons from non-neuronal cell types, for example, by contacting the cell or cell culture medium with one or more agents which inhibit Activin and/or PLKl signaling. Also disclosed are methods for promoting neuron survival, for example, by inhibiting Activin and/or PLKl signaling, and methods for promoting the survival of intermediates in a cell differentiation pathway, for example, by inhibiting Activin and/or PLKl signaling.